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Applied Bioinformatics Chemoinformatics

The document provides an overview of applied bioinformatics and chemoinformatics techniques, tools and opportunities. It discusses topics like genetic engineering, sequencing, bioinformatics databases and tools, applications in biotechnology and biopharmaceutical industries, and current trends and career opportunities in bioinformatics.

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maroua larhni
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40 views

Applied Bioinformatics Chemoinformatics

The document provides an overview of applied bioinformatics and chemoinformatics techniques, tools and opportunities. It discusses topics like genetic engineering, sequencing, bioinformatics databases and tools, applications in biotechnology and biopharmaceutical industries, and current trends and career opportunities in bioinformatics.

Uploaded by

maroua larhni
Copyright
© © All Rights Reserved
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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Applied Bioinformatics & Chemoinformatics:

Techniques, Tools and Opportunities.

FATOKI, Toluwase H.
Department of Biochemistry,
Federal University of Technology, Akure, Nigeria.
+2347032219821
[email protected]
www.linkedin.com/in/hezekiahfatoki
www.fheztbioinformatics.wordpress.com
“None of us is as smart as all of us” – Ken Blanchard.
“If you want to go fast, go alone. If you want to go far, go together.” – African Proverb.
OUTLINES
• Introduction to Genetic Engineering
• Sequencing: The Next Generation
• Introduction to Bioinformatics
• Overview of Bioinformatics in Africa
• Essential Bioinformatics
• Introduction to Database and Tools
• Introduction to Chemoinformatics/Pharmacoinformatics
• Applications of Bioinformatics
• Application in Biotechnology Industries
• Application in Biomedical and Biopharmaceuticals Industries
• Current Trends and Opportunities
• Questions and Answers
Introduction to Genetic Engineering

• The Central Dogma

• Concept Maps of Genetic Engineering


Sequencing: The Next Generation
A Life Decoded is the story of this singular milestone in our history, told by the man
who through a combination of vision, tenacity, ingenuity, and insight challenged
conventional wisdom and refuted his critics to reveal the human genetic code.

Desmond S. T. Nicholl, (2008). An Introduction to Genetic Engineering. Cambridge University Press, New York.
Introduction to Bioinformatics
Overview of Bioinformatics in Africa
Desmond S. T. Nicholl, (2008). An Introduction to Genetic Engineering. Cambridge University Press, New York.
Medha Bhagwat, PhD. NIH Library Bioinformatics Support Program
Essential Bioinformatics
• Section I: Introduction And Biological Databases
• Section II: Sequence Alignment
• Section III: Gene And Promoter Prediction
• Section IV: Molecular Phylogenetics
• Section V: Structural Bioinformatics
• Section VI: Genomics and Proteomics

Arthur M. Lesk,(2002). Introduction to Bioinformatics, Oxford University Press, New York


Introduction to Databases and Tools
http://www.cbs.dtu.dk/biotools/
http://molbiol-tools.ca/molecular_biology_freeware.htm
http://www.hpc.cam.ac.uk/compbio/software
http://bioinformaticssoftwareandtools.co.in/bio_tools.php
http://www.bioafrica.net/software.php
• NCBI: The National Center
for Biotechnology
Information (USA):
http://ncbi.nlm.nih.gov
• EBI:The European
Bioinformatics Institute:
www.ebi.ac.uk
• SIB:The Swiss Institute of
Bioinformatics
Expasy (Expert Protein
analysis system):
www.expasy.org
• Canadian Bioinformatics
Resource
http://cbr-rbc.nrc-cnrc.gc.ca/
Chemoinformatics/Pharmacoinformatics
The computational methods for in silico drug discovery have been broadly
categories into two fields bioinformatics and chemoinformatics.
In case of bioinformatics, major emphasis is on identification and validation
of drug targets, mainly based on functional/structural annotation of genomes.
In case of cheminformatics or pharmacoinformatics, major emphasis is on
designing of drug molecules or ligands and their interaction with drug targets.
Frank K. Brown (1998) defined Chemoinformatics as the mixing of
information resources to transform data into information, and information
into knowledge, for the intended purpose of making better decisions faster in
the arena of drug lead identification and optimization.
https://fheztbioinformatics.wordpress.com/2017/02/04/bioinformatics-chemoinformatics-and-drug-discovery/

Darren Green, (2016). Computational Drug discovery.


APPLICATIONS OF BIOINFORMATICS
Application in Biotechnology Industries

Desmond S. T. Nicholl, (2008). An Introduction to Genetic Engineering. Cambridge University Press, New York.
Application in Biomedical and
Biopharmaceuticals Industries

Desmond S. T. Nicholl, (2008). An Introduction to Genetic Engineering. Cambridge University Press, New York.
Jurgen Drews (2000). Drug Discovery: A Historical Perspective, Science/Drug Discovery, vol.287, 1960-1964.
Current Trends and Opportunities
Jobs, PhDs and Networks
http://blog.biogem.org/2013/03/bioinformatics-carrer-opportunities.html
http://www.sib.swiss/about-us/careers
http://www.nature.com/naturejobs/science/jobs?q=bioinformatics
http://www.bioinformatics.org/jobs/
http://www.linkedin.com/topic/bioinformatics
http://www.linkedin.com/topic/computational-biology
Online Courses
https://www.futurelearn.com
https://www.coursera.org

Thanks
for
listening

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