1.introduction To Biostatistics
1.introduction To Biostatistics
MADIHA IQBAL
Biostatistician
[email protected]
Objectives
• To give best understanding of basic terms
and sampling techniques
History of Statistics
• The word statistics seems to have been
derived from the Latin word status or the
Italian word statist.
• Both these words mean a political state.
The word statist (Milton in the sense of a
statesman, i.e. a person well-versed in the
affairs of the state)
Modern Era
• Modern concept of statistics was
illustrated by Sir R. A. Fisher (1890-1962),
• J. Neyman (1894-1983),
• E. S. Pearson (1895-1981) and many
others.
Defination of statistics
Statistics is defined as.
• According to the croxton and cowdown
"statistics" may be defined as the science
of collection, presentation, analysis and
interpretation of numerical data"
• "Numerical facts systematically arranged"
• Statistical method to summarize the data
and use statistical procedure to reach
certain conclusion
In simple meanings
Statistics is defined as.
• Numerical facts systematically arranged
• As a discipline
• Plural of Statistic
Why we use Statistics
Collection
Interpretation of data
STATISTICS
Organization
Conclusion
Summarization
Analysis
Types of Bio-Statistics
Statistics
Descriptive Statistics Inferential Statistics
Confounding Variables
(that effects both the independent and
dependent variables and thus confuse the
result)
Constant Variables
(Any value that does not but remain fixed
called constant)
Variables & Constants
• Age Variables
• Weight
• Height
• Severity of Pain
• Salary
• Value of “g”
Constants
• Value of “pai”
QUALITATIVE QUANTITATIVE
Types of Variable
Catagorical Discrete
Attribute Countinuous
Types of Variables
QUANTITATIVE VARIABLES
(used to describe or measure the factors that are assumed to cause
or at least to influence the problem) OR (Can be xpressed as
non-numarically) example ; age, height, weight
QUALITATIVE VARIABLES
(that gets modified under the influence of some other variable) OR
(Can be xpressed as non-numarically) example; sex, status,
education
DISCRETE VARIABLES
(veriables which represent in count data) example ; person in
room number of death
COUNTINUOUS VARIABLES
(it can takes on any value fractional or integral with the give
interval) example; age of children , height of the students
Please can you give some
examples of variables???
Types of Variables
Independent Variables
(used to describe or measure the factors
that are assumed to cause or at least to
influence the problem)
OR "which is responsibel for
change"
Dependent Variables
(that gets modified under the influence of
some other variable)
OR "The response of an indepndent
variable is called"
For Example
Cause Effect/ outcome
Independent variable Dependent variable
Other Factors
(Confounding Variables)
For Example
A relationship is shown between the low level of mother’s education and
malnutrition in under 5’s. However, family income may be related to the
mother’s education as well as to malnutrition
Family Income
(Confounding Variables)
Examples
• In a study of a prevalence of a disease in
different age groups, the presence of the
disease may be referred to as a dependent
variable, whereas age is an independent
variable.
• In a study of an association between birth weight
of a child, gestation period(weeks) and smoking
status are possible factors which may influenced
the birth weight of a child. Birth weight is
dependent variable whereas smoking status and
gestation period are independent variables.
Example
• In the study of early sitting, smiling and walking
of a child, the factors such as age, gender, birth
weight, type of feeding, education of mother and
father, birth order, number of siblings, etc. are
independent variables.
Distinctiveness * * * *
Ordering * * *
Equal Interval * *
Absolute Zero *
Data Collection
Data and it’s Types
What is data???
• Closed Questions
» Pr-assigned choices
Questions should be
• Simple (it is best to avoid the statements)
• Avoid asking more than one question
– Do you have temperature and pain
• Avoid from technical terms
• Watch out ambiguity
– Old people should be encouraged to
exercise; but how old is old
Questions should be
• Avoid from leading questions
– How often do you exercise: respondent
should be exercised
• Level of language
The most important note
1. Information collected in a
questionnaire should be based on and
limited to the objective of the study
2. It should be pre-tested for large and
expensive studies
Data collection methods
Sampling Methodology
Population & Sample
Population & Sample
• Parameter: A calculated value from
Population
1. Probability Sampling
– Subjects have equal chance of selection
2. Non-probability sampling
– Subjects of un-equal chance of selection
Probability Sampling