The document discusses the composition and functions of the cell membrane. The cell membrane is made up of a lipid bilayer, proteins, and carbohydrates. It functions to protect the cell, maintain cell potential, and selectively transport substances in and out through channel proteins and carrier proteins.
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Cell Membrane and Its Functions
The document discusses the composition and functions of the cell membrane. The cell membrane is made up of a lipid bilayer, proteins, and carbohydrates. It functions to protect the cell, maintain cell potential, and selectively transport substances in and out through channel proteins and carrier proteins.
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Cell membrane and its functions
Composition of Cell Membrane
Outer covering of the cell that isolates individual cell from its neighbors. It is a dynamic structure and semi permeable. Basic structure is made up of : Lipid bilayer. Proteins. carbohydrates. Lipids
Main lipids in the cell membrane are phospholipids and
cholesterol. Phospholipids: phospholipids molecules have head end with phosphate part and soluble in water i.e , polar , hydrophilic and a tail end made up of fatty acids and it is water insoluble that is non polar and hydrophobic. Hydrophilic ends are directed towards inner and outer surfaces of lipid bilayer and contact with aqueous environment. Lipids
Hydrophobic ends meet in the center of the
membrane. Phospholipidsare not attached to any structure and each molecule is free to move. Thisallow free movements of both lipids and proteins of the cell membrane. Lipid bilayer is highly flexible fluid in nature. cholesterol
Cholesterol is dispersed through out cell membranes , in
the irregular spaces between the hydrophobic tails of the membrane lipids. It makes the membrane stiff and gives it strength. Proteins
Two types of proteins are present in the cell membrane.
Peripheral proteins. Integral proteins. Peripheral proteins; These are attached to inside or outside the lipid bilayer. Integral proteins; These cross the whole thickness of the lipid bilayer. Many of the integral proteins provide structural channels Proteins
through which water molecules and water soluble substances
can defuse between the ECF and ICF like ions. These proteins also have selective properties that prefer the diffusion of some substances over others. Some integral proteins act as carrier proteins that transport substances across the cell membrane. Some times these carrier proteins even transport substances in the direction opposite to their electro chemical gradients for diffusion which is called “active transport”. Proteins
some proteins act as enzymes.
These proteins can also serve as receptors for water soluble chemicals such as peptides hormones and receptors for drugs. Carbohydrates (glycocalyx)
On external surface of cell membrane , membrane
proteins and lipids are conjugated with short chains of poly saccharides. This layer formed is called glycocalyx. The carbohydrates attach to the outer surface of the cell have several important functions ; • Many of them have negative electrical charge which gives most cells an overall negative surface charge that repels other negatively charged objects. Carbohydrates (glycocalyx)
• Formation of inter cellular adhesion.
• Many of the carbohydrates act as receptor substances for binding hormones such as insulin when bound this combination activates attached internal proteins that in turn activate cascade of inter cellular enzymes. Function
It protects and supports cell components and separates
ECF from ICF. Membrane is permeable to lipid soluble substances like O2, CO2 and alcohol while water soluble substances like some ions glucose and urea cross it via channel pumps or with the help of carrier proteins. Helps to maintain the cell potential contains receptors for the chemical and drugs involve in chemical reaction through enzymes.