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Acridine & Indole

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Aravindh
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179 views30 pages

Acridine & Indole

Uploaded by

Aravindh
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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Unit-IV : CONTENT

Properties, synthesis, reactions & medicinal uses of…


ACRIDIN
E
Properties
1. Aromatic

201 167
ACRIDIN
E
Synthesis
1. From diphenyl amine-2-carboxylic acid

201 168
ACRIDIN
E
Synthesis
2. Bernthsen acridine
synthesis

201 169
ACRIDIN
E
Reactions
1. Electrophilic addition to
N

201 170
ACRIDIN
E
Reactions
2. Electrophilic aromatic
substitution

201 171
ACRIDIN
E
Reactions
3. Reduction
reactions

201 172
ACRIDIN
E
Reactions
4. Oxidation

201 173
ACRIDIN
E
Reactions
5. Nucleophilic substitution

201 174
ACRIDIN
E
Medicinal uses

201 175
INDOL
E
Properties
1. Aromatic

201 176
INDOL
E
Synthesis
1. Fischer indole synthesis

201 177
INDOL
E
Synthesis
1. Fischer indole synthesis
Mechanism

201 178
INDOL
E
Synthesis
1. Fischer indole synthesis
Mechanism

201 179
INDOL
E
Synthesis
1. Fischer indole synthesis

201 180
INDOL
E
Synthesis
2. Bischler–Möhlau indole
synthesis

201 181
INDOL
E
Synthesis
3. Madelung synthesis

201 182
INDOL
E
Synthesis
3. Madelung synthesis
E.g.

201 183
INDOL
E
Reactions
1. Electrophilic addition to
N

201 184
INDOL
E
Reactions
2. Electrophilic aromatic
substitution

201 185
INDOL
E
Reactions
2. Electrophilic aromatic
substitution

201 186
INDOL
E
Reactions
2. Electrophilic aromatic
substitution

201 187
INDOL
E
Reactions
2. Electrophilic aromatic
substitution

201 188
INDOL
E
Reactions
2. Electrophilic aromatic
substitution

201 189
INDOL
E
Reactions
3. Reduction
reactions

201 190
INDOL
E
Reactions
4. Nucleophilic substitution

201 191
INDOL
E
Medicinal uses
(1) Indole alkaloids :

201 192
INDOL
E
Medicinal uses

201 193
INDOL
E
Medicinal uses

201 194

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