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Cell
Structures and Functions Human cells vary in size, shape, and function.
Ourcells function interdependently
to maintain homeostasis. Cell Structure the major parts of a cell are: the cell membrane, nucleus (except mature RBCs), cytoplasm, and cell organelles Cell membrane theselectively permeable boundary of the cell. Phospholipids permit diffusion of lipid- soluble materials. Cholesterol provides stability. Proteins form channels, transporters, “self” antigens, and receptor sites for hormones or other signaling molecules. Nucleus the control center of the cell; has a double- layer membrane. Nucleolus—forms ribosomal RNA. Chromosomes—made of DNA and protein; DNA is the genetic code for the structure and functioning of the cell. A gene is a segment of DNA that is the code for one protein. Human cells have 46 chromosomes, and their genetic information is called the genome. Cytoplasm and Organelles Cytoplasm a watery solution of minerals, gases, and organic molecules; contains the cell organelles; site for many chemical reactions. Cell organelles intracellular structures with specific functions Cellular Transport Mechanisms the processes by which cells take in or secrete or excrete materials through the selectively permeable cell membrane Diffusion movement of molecules from an area of greater concentration to an area of lesser concentration; occurs because molecules have free energy: They are constantly in motion. Oxygen and carbon dioxide are exchanged by diffusion in the lungs and tissues. Osmosis the diffusion of water. Water diffuses to an area of less water, that is, to an area of more dissolved material. The small intestine absorbs water from digested food by osmosis. Isotonic, hypertonic, and hypotonic Facilitated diffusion transporters (carrier enzymes) that are part of the cell membrane permit cells to take in materials that would not diffuse by themselves. Most cells take in glucose by facilitated diffusion. Active transport A cell uses ATP to move substances from an area of lesser concentration to an area of greater concentration. Nerve cells and muscle cells have sodium pumps to return Na ions to the exterior of the cells; this prevents spontaneous impulses. Cells of the small intestine absorb glucose and amino acids from digested food by active transport. Filtration pressure forces water and dissolved materials through a membrane from an area of higher pressure to an area of lower pressure. Tissue fluid is formed by filtration: Blood pressure forces plasma and dissolved nutrients out of capillaries and into tissues. Blood pressure in the kidney capillaries creates filtration, which is the first step in the formation of urine. Endocytosis Phagocytosis a moving cell engulfs something; white blood cells phagocytize bacteria to destroy them. Pinocytosis a stationary cell engulfs small molecules; kidney tubule cells reabsorb small proteins by pinocytosis Cell Division Mitosis Meiosis PARENT CELL : original cell that undergone cell division to replicate itself DAUGHTER CELL : newly formed cell after cell division DIPLOID : 46 chromosomes HAPLOID : 23 chromosomes Mitosis one cell with the diploid number of chromosomes divides once to form two cells, each with the diploid number of chromosomes (46 for humans). DNA replication forms two sets of chromosomes during interphase. Stages of mitosis: prophase, metaphase, anaphase, and telophase. Cytokinesis is the division of the cytoplasm following telophase. Mitosis is essential for growth and for repair and replacement of damaged cells. Most adult nerve and muscle cells seem unable to divide; their loss may involve permanent loss of function. PROPHASE METAPHASE ANAPHASE TELOPHASE Meiosis one cell with the diploid number of chromosomes divides twice to form four cells, each with the haploid number of chromosomes (23 for humans). Oogenesis in the ovaries forms egg cells. Spermatogenesis in the testes forms sperm cells. Fertilization of an egg by a sperm restores the diploid number in the fertilized egg. -END-