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BROMIDS
POISONING ALLOPATHIC USES
1.Occasionally used as an escarotic.
2. Internally the bromids are used as sedatives, hypnotics and antispasmodics in acute specific fevers, acute alcoholism, mania, hysteria, infantile convulsions, whooping cough, hypochrondriasis, general nervousness, sexual over excitement, gastro-intestinal disorders of reflex origin, and epilepsy. TOXICOLOGY
• The salts of bromin most commonly used are potassium, ammonium
and sodium bromid. • These salts act as depressants and narcotics, particularly to the brain and nervous system. • They lessen the sensitiveness of the nerves and their conductivity and are also powerful depressants on the heart and sex organs, often causing loss of sex power. • The drug exhibits a special affinity for the brain and sympathetic nervous system. • A very noticeable symptom of chronic bromid poisoning is a peculiar acne form rash. • The eruptions on the face and neck may turn into abscesses and ulcers. Frequently the victims of bromism exhibit erythema and copper colored blotches. • Mental symptoms are very prominent, there being a distinct action on the blood vessels of the brain; these blood vessels contract causing anemia and atrophy of tissues, weakening and loss of memory, defective coordination of muscular activity, difficulty in walking and tremor of the limbs. SYMPTOMS OF BROMISM
• Brom-acne, so common in drugged epileptics—is in turn treated with
arsenic. • Yellowish discoloration of skin with formation of blisters. • Catarrh. Salivation. • Headache, dizziness and general depression. • Impotence. • Diminished reflex excitability. • Neuro-muscular weakness, especially of lower extremities. • Premature senility, paralysis, insanity, loss of self consciousness ELIMINATION OF DRUG IN HEALING CRISIS
1. Elimination occurs mainly through Kidneys leads to increased
urination. 2. Salivary glands, mucoid accumulations in the mouth. 3. Mucous membranes, acute catarrhal elimination. 4. Skin in form of brom-acne 5. Abnormal perspiration, nose bleed, diarrhoea. SIGNS IN THE IRIS
White crescent in region of brain and white wreath in outer margin
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