Slides 2
Slides 2
20Kb
The PLUNC gene family share similar sized exons
The table gives the exon sizes for the human PLUNCs genes along with
those of BPI, LBP, PLTP and CETP.
2005 version - more ESTs and better genomic predictions
Sequenced 50,00 lung derived Ests to generate a lung
transcriptome.
Peptide : ENSMUSP00000028984
Peptide sequence Peptide properties
>ENSMUSP00000028984
MHLLWRLLVLLLGLLALPSALPKQPWPGLTKAHKDGRSTLARIIAQGLLKLNAEGRIQSMRLLDRLNVSG
TVAPGMVGWLIGGMNFQQQQEISINITNVQLDCGGIQMAFPKEWFSANITLEFDIEFKLPFNSNIIKTHA
CMGLTAESWLEKDEFGRRELVMGRCRMEPSSGGASMSTEETSPKMKHFLHNLRESLGKVIPNLVESQVCP
LIGEILRQLDVKLLKGLV
Wt SPLUNC3
+
+
Mouse SPlunc3 transcripts are also found in Testes
(and tracheal) RNA
Trachea
Testes
Wt mSPLUNC3
Increased BPI expression
was found by microarray
analysis.
This is the first indication of
non-neutrophil expression of
BPI