lecture_4.3_science_sy24-25
lecture_4.3_science_sy24-25
NDOCRINE SYSTEM
• Endocrine system is a network
of glands that produce and
release chemical substances
which regulate body functions.
−An endocrine gland is a
ductless gland that produces
and releases a chemical
substance directly into the
bloodstream.
−A hormone is a chemical
substance produced and
released by an endocrine
gland. which activates a
specific organ in the human
body.
Pineal Gland
Hypothalamus
Pituitary Gland
Thyroid Gland
Parathyroid Gland
ENDOCRINE GLAND
• Pineal Gland
−Location : middle of the brain
−Hormone
Melatonin : regulates sleep
cycle
• Hypothalamus
−Hypothalamus is the gland that
controls the pituitary gland.
−It stimulates or suppresses
hormone secretions from the
pituitary gland.
−Location : lower central part
of the brain
−Hormone
Growth-hormone-releasing
hormone (GHRH) :
stimulates the release of
growth hormone (GH) from
the pituitary gland
Corticotropin-releasing
hormone (CRH) : stimulates
the release of
adrenocorticotropic
hormone (ACTH) from the
pituitary gland
Thyrotropin-releasing
hormone (TRH) : stimulates
the release of thyroid-
stimulating hormone (TSH)
from the pituitary gland
Gonadotropin-releasing
hormone (GnRH) : stimulates
the release of follicle-
stimulating hormone (FSH)
and luteinizing hormone (LH)
from the pituitary gland
• Pituitary Gland
−Pituitary gland is known as
the master gland.
−Location : base of the brain,
beneath the hypothalamus
−Hormone
Growth hormone (GH) :
stimulates the growth of
bones and other body tissues
plays a role in the body’s
handling of nutrients and
minerals
Adrenocorticotropic hormone
(ACTH) or corticotropin :
stimulates the adrenal glands
to secrete glucocorticoids
such as cortisol
Thyroid-stimulating hormone
(TSH) or thyrotropin :
stimulates the thyroid gland
to secrete thyroxine and
triiodothyronine
Follicle-stimulating hormone
(FSH) : stimulates egg
production in females and
sperm production in males
and stimulates estrogen
secretion in females
Luteinizing hormone (LH) :
initiates ovulation and
stimulates progesterone
secretion in females and
testosterone in males
Prolactin : stimulates
mammary gland growth and
milk production in females
Endorphin : acts on the
nervous system
reduces feeling of pain
Antidiuretic hormone (ADH)
or vasopressin : controls the
balance of water in the body
promotes reabsorption of
water by the kidneys
Oxytocin : triggers the
contraction of the uterus in a
woman to induce labor
• Thyroid Gland
−Location : front part of the
lower neck
−Hormone
Thyroxine and
triiodothyronine : control
the rate at which cells burn
fuels from food to produce
energy (body metabolism)
Calcitonin: causes storage
of calcium in bones
lowers blood calcium level
• Parathyroid Glands
−Location : attached to the
thyroid gland
−Hormone
Parathyroid hormone :
regulates the level of
calcium in the blood
raises blood calcium level
• Thymus
−Location : between the lungs
−Hormone
Thymosin : stimulates the
development of disease-
fighting cells (antibodies)
• Adrenal Glands
−Location : on top of the kidney
−Hormone
Aldosterone : causes sodium
and water to be retained in the
body and increases the rate at
which potassium is eliminated
Cortisol : increases the
breakdown and conversion of
carbohydrate, protein and fats
to energy forms that can be
used by the body
reduces inflammatory and
immune responses
Epinephrine (adrenaline) and
norepinephrine
(noradrenaline) : known as
fight-or-flight hormones that
prepare the body for vigorous
physical activity
• Pancreas (Islets of Langerhans)
−Location : between the kidneys
−Hormone
Insulin : lowers blood glucose
level
glucose is converted to
glycogen and stored in the
liver and muscles
Glucagon : raises blood glucose
level
glycogen is converted to
glucose
• Ovaries
−Location : pelvis
−Hormone
Estrogen : promotes
development and maintains
female secondary sex
characteristics
stimulates uterine lining
growth
Progesterone : stimulates
uterine lining growth
• Testes
−Location : scrotum
−Hormone
Testosterone : supports
sperm formation
promotes development
and maintains male
secondary sex
characteristics