DOES BLOOD GROUP AFFECT HEMOGLOBIN LEVELS AMONG BLOOD DONORS IN INDIA -

A RETROSPECTIVE OBSERVATIONAL STUDY FROM A TERITIARY CARE CENTER

AIMS & OBJECTIVES: RESULTS: Of the 857 donors, 170(20%) were A group donors, 272(32%) B, 370(43%) O and 44(5%) were
The aim of the study is to find the effect of donor age and blood group on of AB group. One donor was Bombay group. Most of our donors(62%) were in the age group of 18-30
hemoglobin levels in Indian donors. A recent study has reported a years. The mean hemoglobin was 14.4 g/dl. The mean (+/- 1 SD) of hemoglobin for A group is 14.44g/dl
significantly higher hemoglobin in blood group B compared to group A (13.37-15.57), 14.43(13.3-15.56) for B group, 14.59 (13.44-15.74) for O group and 14.47 g/dl (13.29-
donors in Germany.(1) 15.65) for AB group. There was no statistically significant difference among the donors of different
blood groups with and without age adjustment. However there was a statistically significant decrease in
METHODS: hemoglobin with age. This can be explained by the fact that as Testosterone decreases with age,
A retrospective study based on donor records at Blood center, Kamineni Erythropoietin and Hemoglobin values also decrease. (2) The low hemoglobin in the 18-20 age group
Hospital, Hyderabad; was carried out over a period of 6 months from compared to the general trend could not be explained.
January 2023 to June 2023. The data from 857 male donors was included 16
Average Hemoglobin of different Blood group donors
& analysed using Microsoft Excel & JASP for age, gender and hemoglobin by age
15.5 15.6
(pre-donation). Determination of Hb content of all donors are done using A B O AB All
HemoCue Hb 301 analyzer. 15 14.84 14.8
Donor Blood groups 14.51 14.57 14.6
Average Hemoglobin by age group 14.5 14.39 14.42 14.32 14.49 14.35
5% 0% 14.61 14.65 14.64 14.48
14.47 14.42 14.16
14.3 14.37
20% 14.59 14 14.11
14.47 13.74
14.44 14.43 13.47
13.5 13.6
43% 14.57
14.42 14.48
14.35
32% 14.16 13

AAgeBgroup
O ofAB
donors
Oh 18-20 21-30 31-40 41-50 51-60 12.5
18-20 21-30 31-40 41-50 51-60
442
CONCLUSION: The present study shows that there is no statistically significant difference in hemoglobin level of different blood groups with and
269 without age adjustment among whole blood donors in India. Young donors having a higher hemoglobin level may be preferred over elder donors which
may result in higher hemoglobin level post transfusion. However, small sample size & inclusion of only male donors may affect the outcome.
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38 20 2 1.Kronstein-Wiedemann R, Blecher S, Teichert M, et al. Novel evidence that the ABO blood group shapes erythropoiesis and results in higher hematocrit for blood
[email protected]
group B carriers. Leukemia. 2023;37(5):1126-1137. doi:10.1038/s41375-023-01858-4
18-20 21-30 31-40 41-50 51-60 >60 2.Ershler WB, Shan S, McKelvey J, Artz AS, Denduluri N, Tecson J, Taub DD, Brant L, Ferrucci L, Longo DL. Serum Erythropoietin and Aging: A Longitudinal Analysis. [email protected]