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CELL BIOLOGY AND GENETICS (Seminar)

Sex linked inheritance refers to traits determined by genes on sex chromosomes, with types including X-linked, Y-linked, and XY-linked inheritance. X-linked traits, such as color blindness and hemophilia, are more common in males due to their hemizygous condition, while Y-linked traits are passed from father to son. Inheritance can be completely or incompletely sex linked, depending on whether crossing over occurs in homologous regions of the chromosomes.
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0% found this document useful (0 votes)
14 views18 pages

CELL BIOLOGY AND GENETICS (Seminar)

Sex linked inheritance refers to traits determined by genes on sex chromosomes, with types including X-linked, Y-linked, and XY-linked inheritance. X-linked traits, such as color blindness and hemophilia, are more common in males due to their hemizygous condition, while Y-linked traits are passed from father to son. Inheritance can be completely or incompletely sex linked, depending on whether crossing over occurs in homologous regions of the chromosomes.
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CELL BIOLOGY

AND
GENETICS
SEX LINKED
SEMINAR INHERITANCE

BY…
S.R.SANTHIYA
SEX LINKED
INHERITANCE

 The inheritance of a trait (Phenotype) that is


determined by a gene located on one of the sex
chromosomes is called sex linked inheritance
 The gene controlled by genes located on the sex
chromosomes is called sex linked inheritance
 It was discovered by T.H.Morgan
TYPES

1. X-LINKED INHERITANCE

2. Y-LINKED INHERITANCE

3. XY-LINKED INHERITANCE
X-LINKED
INHERITANCE

 Certain sex linked genes are located only on X


chromosome and their alleles are absent from Y
chromosome
 These genes are called X linked genes the
characters controlled by these genes are called X
linked characters and their mode of inheritance is
called X linked inheritance
 E.g: Colour blindness, Haemophilia
COLOUR BLINDNESS

 Colour Blindness is a sex linked character


discovered by Wilson in 1911.
 Hereditary disease and the affected person cannot
distinguish between red and green colour.
 Red blindness is called Protonopia and green
blindness is called Deutronopia.
 Normal person contains genes CC or Cc or C alone.
• The genes for colour blindness are located on the
X chromosome their alleles are not present on Y
chromosome.

• So man has only one gene.The presence only one


gene for a character is called hemizygous.So
man is hemizygoute for colour blindness.

• This Character is common in man then in woman.

• Follws criss-cross Inheritance.

• Never transmitted to son from father.

• Daughter carrying one recessive gene for colour


blindness is called carrier.
HAEMOPHILIA

 Also called as Bleeders disease.


 Characterized by delayed blood clotting.
 This is because of the absence of anti
haemophilic globulin which plays an important
role in blood clotting.
 In normal person,blood clots in 2 to 8 minutes
but in haemophilic patients clotting delayed for
20 minutes to 24 hours .Hence they bleed
continuously from the wound.
• Queen Victoria was also affected by this disease it was
transmitted to her descendants.

• Hence this disease is common among the royal family of


Queen Victoria and so it is also called as royal disease.

• It is a sex linked recessive characters.

• Caused by recessive gene represents as hh and normal


condition due to dominant gene H.

• The genes are located on X chromosome.

• Male is homozygoute.

• Disease is common in male then female.


• Follows criss –cross inheritance.

• Generally haemophilic patients will die before


reaching
reproductive stage.
Y-LINKED INHERITANCE

 The sex linked genes are located on Y


chromosome are called Y linked genes.
 The Y linked genes are Holandric genes.
 The genes are transmitted directly from
father to the son.
 Their mode of inheritance is called Y linked
inheritance.
 E.g:Hyperterichosis,Ichthyosis hysterix.
XY- LINKED INHERITANCE

 Certain sex linked genes are located on both X and Y


chromosomes.

 They are called XY linked genes and their mode of


inheritance is called XY linked inheritance.

 E.g:Xeroderma pigmentosum, nephritis,retinitis


pigmentosa etc,.
COMPLETELY SEX LINKED
INHERITANCE

 The X and Y chromosome are not similar.


 X chromosomes is larger than Y chromosomes.
 The lower part of both the chromosomes are similar
these two parts are called homologous regions .They
have same type of genes.
 The genes located on non-homologous regions in
together because crossing over does not occur in these
regions.
• The genes located on non-homologous regions are
called completely sex linked genes and their
inheritance is
called completely sex linked inheritance.

• E.g: Haemophilia, Colour blindness.


INCOMPLETELY SEX LINKED
INHERITANCE

 Thegenes are homologous regions of sex


chromosomes do not inherit together because
crossing over may occur in these regions.
 So,these genes are called incompletely sex
linked genes and their mode of inheritance is
called incompletely sex linked inheritance.
 E.g: Retinitis pigmentosa, nephritis.

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