Medical Termination of Pregnancy
Medical Termination of Pregnancy
OF PREGNANCY
MEDICAL TERMINATION
OF PREGNANCY
THE MEDICAL OR SURGICAL TERMINATION OF PREGNANCY BEFORE THE
PERIOD OF VIABILITY OF FETUS.
MEDICAL TERMINATION OF
PREGNANCY(MTP) ACT
There are very few contraindications but one needs to be very careful in
performing MTP in the following conditions.
1. Medical disorders like heart disease
2. Suspected ectopic pregnancy or undiagnosed adnexal mass
3. Chronic renal failure
4. Hematological disorders
5. Allergy to any drugs used
METHODS OF TERMINATION OF
PREGNANCY
First Trimester (Up to 12 Weeks)
Medical-
Mifepristone alone- less effective
Misoprostol alone- less effective
Mifepristone and misoprostol (PGE1 )- most commonly used,
It is effective up to 63 days and is highly successful when used within 49
days of gestation.
Methotrexate and misoprostol-Methotrexate 50 mg/m2 IM (before 56
days of gestation) followed by 7 days later misoprostol 800 µg vaginally
is highly effective.
Methotrexate and misoprostol regimen is less expensive but takes longer
time than mifepristone and misoprostol.
PRE-REQUISITES FOR MEDICAL
ABORTION
1. Falling within the defined criteria for the medical abortion especially
gestational age.
2. There should be no medical contraindication.
3. Good support system in case of need of surgical evacuation or any
complication.
4. Ability to follow-up visits.
5. Patient should be willing for it.
Patient should be informed that if medical method fails, she will have to
undergo surgical evacuation as the drugs are teratogenic.
Counselling of the patient is very important.
All formalities like filling MTP form and taking consent are like that of
surgical evacuation.
Side-effects of Medical Methods
1. Cramping pain
2. bleeding -Median blood loss is less than 100 mL, although the range can
extend up to several hundred milliliters and is significantly correlated with
the period of gestation.
3. About one-third of patients complain of nausea, vomiting, diarrhea.
4. dizziness or fatigue.
Contraindications
IMMEDIATE:
(1) Injury to the cervix (cervical lacerations).
(2) Uterine perforation during D&E.
(3) Hemorrhage and shock due to trauma, incomplete abortion, atonic uterus or
rarely coagulation failure.
(4) Thrombosis or embolism.
(5) Postabortal triad of pain, bleeding and low-grade fever due to retained clots
or products. Antibiotics should be continued, may need repeat evacuation.
(6) Related to the methods employed:
Prostaglandins—intractable vomiting, diarrhea, fever, uterine pain and
cervicouterine injury.
Oxytocin—water intoxication and rarely convulsions
Hysterotomy
COMPLICATION OF MTP
REMOTE:
menstrual disturbances
chronic pelvic inflammation
infertility due to cornual block
scar endometriosis (1%)
uterine synechiae leading to secondary amenorrhea.
recurrent mid trimester abortion due to cervical incompetence,
ectopic pregnancy (threefold increase),
preterm labor,
rupture uterus,
Rh-isoimmunization in Rh-negative women, if not prophylactically protected with
immunoglobulin and
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