The document summarizes efforts to improve health workforce performance and systems at the district management level in Tanzania. Key health indicators related to HIV/AIDS treatment improved dramatically from 2010 to 2011. The role of district management was strengthened across six domains including management, supply chains, planning, and human resources. Initiatives like improved orientation for new staff led to substantially higher retention rates. Lessons highlighted the importance of empowerment and how district management intersects with health systems strengthening. Next steps focused on continuing quality improvement and exploring their role as change agents.