Gleb Natapov presents on using in-memory storage in ScyllaDB to provide faster access times compared to disk-based storage. He discusses how ScyllaDB uses SSTables that are stored on disk by default, which can incur latency penalties during cache misses. Natapov introduces new in-memory and mirror file types that allow storing SSTable contents directly in RAM to avoid disk access latency. He demonstrates how to configure ScyllaDB to reserve RAM for in-memory storage and to create tables specifying the in-memory option to gain predictably low latency performance.