Combine is Apple's new reactive framework for declarative processing of asynchronous operations using publishers and subscribers. It streamlines asynchronous code by allowing developers to tell the machine what they want to happen rather than how to do it. Combine integrates with existing frameworks and is used heavily in SwiftUI. Publishers send values to subscribers, and Combine provides many built-in publisher types for common asynchronous tasks like network requests. Asynchronous code written with Combine is more organized, readable, and maintainable compared to previous approaches.