This document summarizes an ISACA conference that took place in October 2016 in San Francisco. It discusses using the CIS Critical Security Controls and NIST Cybersecurity Framework to achieve cyber threat resilience through tools and automation. It also covers assessing baseline configurations of systems and environments to measure compliance with frameworks like CIS Benchmarks, DISA STIGs, NIST CSF and identifying gaps to prioritize remediation. Lastly, it emphasizes that most cyberattacks can be prevented by maintaining secure baseline configurations of devices and software through continuous monitoring and vulnerability management.