This document describes several practical experiments conducted using the WinDLX and WinMIPS64 simulators. It begins with an introduction to the DLX processor and WinDLX simulator. It then outlines 6 practical experiments: 1) Using WinDLX to calculate factorials, 2) Writing a prime number program in WinDLX, 3) Writing a program to calculate z=(x^2+y^2)*(x+y) in WinDLX, 4) Studying the WinMIPS64 simulator, 5) Implementing register swapping in WinMIPS64 without a third variable, and 6) Writing a program to calculate x^n in WinMIPS64. For each experiment, the document provides the program