This document compares two methodologies for malware analysis: MARE and SAMA. MARE was the first structured malware analysis methodology, introduced in 2010, and consisted of four phases: detection, isolation/extraction, behavioral analysis, and code analysis/reverse engineering. SAMA was introduced more recently in 2020 to address challenges posed by increasingly sophisticated malware. It retains the same four phases but renames and restructures them. The document analyzes the phases of each methodology and compares their approaches. It finds that SAMA's initial phase of establishing an analysis environment before beginning analysis is preferable to MARE's approach of starting with detection.