Constructors and destructors are special member functions in C++ that are used to initialize and cleanup objects. Constructors are called automatically when an object is created and are used to set initial values for object attributes. Destructors are called automatically when an object is destroyed and can perform cleanup tasks. There are different types of constructors like default, parameterized, and copy constructors. Constructors and destructors have the same name as the class but constructors don't have a return type while destructors are preceded by a tilde (~).