Kubernetes in Production, From the Ground Up discusses setting up a Kubernetes cluster from scratch using CoreOS, etcd, Docker, and Terraform. The document outlines setting up etcd for high availability using an autoscaling group, configuring the Kubernetes master nodes to run the API server, scheduler, and controller manager as pods, and deploying worker nodes that run the kubelet to join the cluster. The process involves using cloud-init scripts, Terraform, and container images to automate the installation and configuration of all cluster components in a scalable and resilient way.