The document provides an overview of CTS2 (Common Terminology Services 2), which is a RESTful framework for managing controlled biomedical terminologies and ontologies. It describes the CTS2 development framework, available implementations, JSON response formats, searching capabilities, use of changesets to manage updates, mapping between code systems, and integration with the BioPortal terminology repository. The goal of CTS2 is to provide a standardized yet flexible service for working with terminologies in a distributed, interoperable manner.