Deep Learning Radial Basis Function Neural Networks Based Automatic Detection of Diabetic Retinopathy
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This document presents a novel approach using deep neural networks, specifically a radial basis function neural network (RBFNN), for the automated detection of diabetic retinopathy through image classification. The proposed system achieved a sensitivity of 95% and an accuracy of 75% on a validation dataset of 5,000 images, utilizing preprocessing, segmentation, and feature extraction techniques. The study indicates that the deep learning model can significantly reduce diagnosis time and improve accuracy compared to traditional manual methods.
![Our Heritage
ISSN: 0474-9030
Vol-68-Issue-1-January-2020
P a g e | 8937 Copyright ⓒ 2019Authors
Deep Learning Radial Basis Function Neural Networks Based
Automatic Detection of Diabetic Retinopathy
J.Friska1
; M. Mano Priya2
1
Associate Professor, Department of Electronics and communication Engineering,
2
PG Scholar, Department of Electronics and communication Engineering,
Francis Xavier Engineering College, Tirunelveli, Tamilnadu, India.
Abstract
In this project, we propose a new novel DNN-based automatic detection of diabetic
retinopathy. In deep neural networks are used for classify the images that indicate diabetic
retinopathy. The main aim of this project is to find the suitable way to detect the problems
and classify them. We propose an deep neural network (RBFNN) classifier gives high
precision in grouping of these disease through spatial examination. The RBFNN classifier
does not require an large training time, therefore the model production can be expedited. We
further find from our data set of 80,000 images used in our proposed RBFNN achieves a
sensitivity of 95% and an accuracy of 75% on 5000 validation images. The fuzzy c means
clustering is used to store the information as the processed images in this project . Finally,
the proposed system is developed using matlab simulation.
Index Terms: Deep neural networks(DNN),Radial basis function neural network (sRBFNN),
Support vector machine(SVM),Gray level co occurrence matrix(GLCM).
Introduction
Nowadays, the diagnosis has still been achieved mainly by manual techniques.
However, the accuracy of it depends on the operator’s expertise. The situation of the operator
may highly affect the analysis. Recently, there are efforts and research studies on making it
automatic the process. The works on automatization can be divided into two parts, namely,
segmentation and classification of diabetic retinopathy. The main objective of the project is to
study, implement, and classify the diabetic retinopathy problem .Since there are a lot of cells
in a diabetic retinopathy, we have to find a suitable way to detect and classify them. The
objective is to compare the sensitivity of diabetic retinopathy problem. The following
methods have some drawbacks and they are discussed.
[1] Background retinopathy occurs when diabetes damages the small blood vessels and
nerves in the retina. The retina acts like the film of the eye. It captures images coming
through the front of the eye and sends them to the brain to see. Fluids leaking from the
damaged vessels cause the retina to swell .Swelling of the macula, the central area of the
retina, can lead to vision loss. [2] In this stage, more severe and widespread changes are seen
in the retina, including bleeding into the retina. At high risk the vision could eventually be
affected. [3] In this stage, new blood vessels and scar tissue have formed on your retina,
which can cause significant bleeding and lead to retinal detachment. At high risk the vision
could be loss.[4]Retinopathy progression appears to follow different patterns. Some patients
develop leakage and other develop capillary closure which also causes loss of sight. The
number of haemorrhages and micro aneurysms indicate progression. If they increase in](https://image.slidesharecdn.com/10z-201108235236/85/Deep-Learning-Radial-Basis-Function-Neural-Networks-Based-Automatic-Detection-of-Diabetic-Retinopathy-1-320.jpg)
![Our Heritage
ISSN: 0474-9030
Vol-68-Issue-1-January-2020
P a g e | 8938 Copyright ⓒ 2019Authors
number the retinopathy is getting worse. Dropping blood pressure to the targets will slow
down progression right away.[5]This approach is used for the task, then produces a program
that can accomplish the task of generating the correct outputs for new input . In this way, we
generate the program by a linear algorithmic process may look completely different than one
developed manually by a programmer, it may contain huge amounts of information about a
[6] A new framework for detecting retinopathy problem using support vector machine is
introduced in this paper. This paper Classify the diabetic retinopathy problem using deep
learning radial neural network classifier. Accuracy is increased by using binary searching
algorithm. Compare the sensitivity of diabetic retinopathy problem using neural network
classifier.
Proposed System
In the proposed work, we would like to propose a methodology using RBFNNs for
classifying the images that indicate diabetic retinopathy (DR). The retina images are from
fundus photography. This photography uses fundus camera to get the color images of interior
surface of the eye so that we can monitor the eye and find the disorders. Fundus camera
contains intricate microscope which attached to a flash-enabled camera. This camera helps to
photograph the interior surface of the eye including retina, macula, and posterior pole.
Currently, the DR detection is a manual and time-consuming process. The patient will go to
clinic to take fundus photograph of the retina and the image will take. He/she will get the
result in 2 or 3 days, and then patient should take the result to an ophthalmologist for the
review. As this traditional way of DR detection takes more time and the chance of
miscommunication and the delayed treatment lead is more, there we can use automatic DR
detection algorithm which can be implemented in fundus camera itself. Here, after taking the
retina image, the image will be given to already trained model which classifies the images
based on whether the patient has DR or not, if he/she has the DR, and then the severity level
of the disease. This helps both the ophthalmologist and patient so that the delayed treatment
would not be happen.
Fig 2.1 Proposed system Block diagram](https://image.slidesharecdn.com/10z-201108235236/85/Deep-Learning-Radial-Basis-Function-Neural-Networks-Based-Automatic-Detection-of-Diabetic-Retinopathy-2-320.jpg)
Deep Learning Radial Basis Function Neural Networks Based Automatic Detection of Diabetic Retinopathy
- 1. Our Heritage ISSN: 0474-9030 Vol-68-Issue-1-January-2020 P a g e | 8937 Copyright ⓒ 2019Authors Deep Learning Radial Basis Function Neural Networks Based Automatic Detection of Diabetic Retinopathy J.Friska1 ; M. Mano Priya2 1 Associate Professor, Department of Electronics and communication Engineering, 2 PG Scholar, Department of Electronics and communication Engineering, Francis Xavier Engineering College, Tirunelveli, Tamilnadu, India. Abstract In this project, we propose a new novel DNN-based automatic detection of diabetic retinopathy. In deep neural networks are used for classify the images that indicate diabetic retinopathy. The main aim of this project is to find the suitable way to detect the problems and classify them. We propose an deep neural network (RBFNN) classifier gives high precision in grouping of these disease through spatial examination. The RBFNN classifier does not require an large training time, therefore the model production can be expedited. We further find from our data set of 80,000 images used in our proposed RBFNN achieves a sensitivity of 95% and an accuracy of 75% on 5000 validation images. The fuzzy c means clustering is used to store the information as the processed images in this project . Finally, the proposed system is developed using matlab simulation. Index Terms: Deep neural networks(DNN),Radial basis function neural network (sRBFNN), Support vector machine(SVM),Gray level co occurrence matrix(GLCM). Introduction Nowadays, the diagnosis has still been achieved mainly by manual techniques. However, the accuracy of it depends on the operator’s expertise. The situation of the operator may highly affect the analysis. Recently, there are efforts and research studies on making it automatic the process. The works on automatization can be divided into two parts, namely, segmentation and classification of diabetic retinopathy. The main objective of the project is to study, implement, and classify the diabetic retinopathy problem .Since there are a lot of cells in a diabetic retinopathy, we have to find a suitable way to detect and classify them. The objective is to compare the sensitivity of diabetic retinopathy problem. The following methods have some drawbacks and they are discussed. [1] Background retinopathy occurs when diabetes damages the small blood vessels and nerves in the retina. The retina acts like the film of the eye. It captures images coming through the front of the eye and sends them to the brain to see. Fluids leaking from the damaged vessels cause the retina to swell .Swelling of the macula, the central area of the retina, can lead to vision loss. [2] In this stage, more severe and widespread changes are seen in the retina, including bleeding into the retina. At high risk the vision could eventually be affected. [3] In this stage, new blood vessels and scar tissue have formed on your retina, which can cause significant bleeding and lead to retinal detachment. At high risk the vision could be loss.[4]Retinopathy progression appears to follow different patterns. Some patients develop leakage and other develop capillary closure which also causes loss of sight. The number of haemorrhages and micro aneurysms indicate progression. If they increase in
- 2. Our Heritage ISSN: 0474-9030 Vol-68-Issue-1-January-2020 P a g e | 8938 Copyright ⓒ 2019Authors number the retinopathy is getting worse. Dropping blood pressure to the targets will slow down progression right away.[5]This approach is used for the task, then produces a program that can accomplish the task of generating the correct outputs for new input . In this way, we generate the program by a linear algorithmic process may look completely different than one developed manually by a programmer, it may contain huge amounts of information about a [6] A new framework for detecting retinopathy problem using support vector machine is introduced in this paper. This paper Classify the diabetic retinopathy problem using deep learning radial neural network classifier. Accuracy is increased by using binary searching algorithm. Compare the sensitivity of diabetic retinopathy problem using neural network classifier. Proposed System In the proposed work, we would like to propose a methodology using RBFNNs for classifying the images that indicate diabetic retinopathy (DR). The retina images are from fundus photography. This photography uses fundus camera to get the color images of interior surface of the eye so that we can monitor the eye and find the disorders. Fundus camera contains intricate microscope which attached to a flash-enabled camera. This camera helps to photograph the interior surface of the eye including retina, macula, and posterior pole. Currently, the DR detection is a manual and time-consuming process. The patient will go to clinic to take fundus photograph of the retina and the image will take. He/she will get the result in 2 or 3 days, and then patient should take the result to an ophthalmologist for the review. As this traditional way of DR detection takes more time and the chance of miscommunication and the delayed treatment lead is more, there we can use automatic DR detection algorithm which can be implemented in fundus camera itself. Here, after taking the retina image, the image will be given to already trained model which classifies the images based on whether the patient has DR or not, if he/she has the DR, and then the severity level of the disease. This helps both the ophthalmologist and patient so that the delayed treatment would not be happen. Fig 2.1 Proposed system Block diagram
- 3. Our Heritage ISSN: 0474-9030 Vol-68-Issue-1-January-2020 P a g e | 8939 Copyright ⓒ 2019Authors 2.1 PRE PROCESSING The input image is preprocessed to remove noise and prepare them to be fed into neural network. Preprocessing the input image in three steps: Color histogram RGB plane Filtering 2.1.1 COLOR HISTOGRAM Here color histogram is also a histogram which even plots a graph of an image in terms of color distribution of that particular image. 2.1.2 RGB PLANE The input image is color image, the color processing steps converts the color image into grayscale image. This operation is done by using the following formula. Y = 0.299*R + 0.587*G + 0.114 2.1.3 GAUSSIAN FILTER Filtering is a process of improving an image. Filtering can highlight some unique features or eliminate some unwanted features. Gaussian filter conserves the edges of an image while minimising nonspecific noises. The most commonly occurring noise is the impulse noise. It introduces at the time of image acquisition and transmission of image is the impulsive noise. Image noise comes from various sources. Noise can be obtained due to communication errors and compression of images. 2.2 SEGMENTATION Segmentation is the process of allocating some labels in to all pixels of the images based on the similarity criteria like pixels with same label to produce meaningful areas of the input image it is used to solve the inaccurate recognition problem. It is the major step in object recognition in the input image. The main aim is to divide the input retina images in to segments. This project propose Fuzzy C-means clustering based method for region based pixel separation 2.3 FEATURE EXTRACTION Feature extraction playing an essential job in sample characterization. Gray level cooccurence matrix (GLCM) is used for feature extraction. The size of GLCM is decided by the Quantities of grey dimension in the image. Extracting the features from 256 samples the blob in the background is detected. 2.4 IMAGE CLASSIFICATION RBFNN is utilized in the proposed work for disease classification. Neural Networks are made out of basic components that are enlivened by organic neuron works in parallel. We train neural system to perform explicit capacity by modifying loads between components. The system is balanced dependent on the correlation with
- 4. Our Heritage ISSN: 0474-9030 Vol-68-Issue-1-January-2020 P a g e | 8940 Copyright ⓒ 2019Authors the yield and the comparing focus until the system yield coordinates the objective. RBFNN classifier depends on two stages, for preparing and testing. Classification exactness relies upon preparing. Results and Discussions This project is implemented using Matlab simulation. 3.1 INPUT IMAGE The figure shows input image for the proposed work. The colour conversion process is used to convert colour image to gray scale image. Fig 3.1 Input image for the proposed system 3.2 GRAY SCALE IMAGE The figure shows input RGB image to gray scale image for the proposed work. This image is given for filtering using Gaussian filter. Fig 3.2 Gray scale converted image for proposed system 3.3 FILTERED IMAGE The figure shows the filtered image.
- 5. Our Heritage ISSN: 0474-9030 Vol-68-Issue-1-January-2020 P a g e | 8941 Copyright ⓒ 2019Authors Fig 3.3 Filtered image for the proposed system 3.4 SEGMENTED IMAGE The figure shows the segmented image for the proposed work.The problem is recognised in this step. Fig 3.4 Segmented image for proposed system 3.5 BLOB BACKGROUND DETECTED The figure shows the blob background detection . Fig 3.5 Blob background detection 3.6 BLOB DETECTED The figure shows the accurate blob detection.
- 6. Our Heritage ISSN: 0474-9030 Vol-68-Issue-1-January-2020 P a g e | 8942 Copyright ⓒ 2019Authors Fig 5.6 Blob detected image 3.7 DETECTED RESULT The figure shows the great outcomes in training time, classification and mean square error. Fig 3.7 Diabetic retinopathy problem identified image Conclusion This project proposed algorithm for automated feature extraction and detection of Diabetic retinopathy provides the robust solution. Results obtained indicate that deep learning can provide a low-cost solution for diagnosing Diabetic retinopathy with consistency. This experiment on large dataset indicates the potential of deep learning based model in diagnosing Diabetic retinopathy accurately from fundus images. Such automated system reduces dependencies on clinicians. Compared to other algorithms, the experimental results prove that the proposed approach can detect and
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