ENGAGE is innovating science education by embedding responsible research and innovation (RRI) in formal learning. It has engaged over 750,000 students, 9,355 teachers, and visitors from 80 countries. The program activates students' interests through dilemma group discussions to develop problem-solving and conversation skills on scientific innovations. Students are given opportunities for self-expression and responsibility to make informed decisions. They learn inquiry skills for RRI combined with science knowledge through inquiry-based projects. Whole-class dialogues develop argumentation skills. Students also assess outcomes by interacting with scientists.