Identification of alcohol content in asava and arista.pptx
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1. The document discusses the preparation and properties of Asava and Arishta, which are Ayurvedic herbal formulations produced through a fermentation process. Key steps include soaking herbs in sugars like honey or jaggery for a specified period of time to allow extraction of active compounds and alcohol generation. 2. Asava and Arishta have several beneficial properties like increased stability, potency, and bioavailability of compounds due to the constant low level of alcohol. They produce rapid therapeutic effects at low doses. 3. The preparation process for Arishta involves making an herbal decoction, adding jaggery or honey, and sealing the mixture in containers for fermentation. Asava preparation skips
![INTRODUCTION -
Asava and Arista
They are the medical preparation processed by soaking the drug [in thepowdered
form or in the form of their decoction(known as Kasaya)] in a solution of sugar
honey ,jaggery. For a specified period of time.
During soaking it undergoes fermentation generating alcohol and in process
facilitating extraction of active constants containing in the drug. Alcohol so
generated also serve as preservative in the products.
Examples : Madhukasava Punarnavasava Arvindasava Lohasava Ashokarishta.](https://image.slidesharecdn.com/ffbhavya-2-230125181340-1f65eeac/85/Identification-of-alcohol-content-in-asava-and-arista-pptx-3-320.jpg)
Identification of alcohol content in asava and arista.pptx
- 2. Contents 1. Introduction 2. Preparation of Asava and Arishta 3. Procedure 4. Calculation 5. Skills required
- 3. INTRODUCTION - Asava and Arista They are the medical preparation processed by soaking the drug [in thepowdered form or in the form of their decoction(known as Kasaya)] in a solution of sugar honey ,jaggery. For a specified period of time. During soaking it undergoes fermentation generating alcohol and in process facilitating extraction of active constants containing in the drug. Alcohol so generated also serve as preservative in the products. Examples : Madhukasava Punarnavasava Arvindasava Lohasava Ashokarishta.
- 4. PROPERTIES OF ASAVA AND ARISHTA 1. These formulations are very stable the bioactive products of fermentation are continuously exposed to low concentration of alcohol. Indeed, the medicinal properties of Asava and Arishta are thought to increase with time. 2. The constant presence of alcohol in these formations may detoxify certain phytochemicals and increase the potency of others. 3. These fermented extract rapid therapeutics effects at low doses. Thus, the aqueous nature of the extract may promote increase uptake of the drug by the target organs. Improvement in the efficiency the extraction of drug molecules from the herbs and it also improves in drug delivery in the human body sites. 4. They are moderately alcoholic (up to 12 % by Volume) and mostly sweetish with slight acidic and agreeable aroma.
- 5. Preparation :Arista Herbs or drug converted into powder (Yavakuta ,churna) Decoction is prepared (Kashya/Kwatha) It is then is strained and kept in safe place in the fermentation vessel or pot. Then jaggery or honey according to the formula is separately dissolved filter and added to the fermenting vessels. Then Prakahupa dravya and Dhataki puspha added and made into find powder then added to vessel . Mouth of vessel is completely covered with an earthen lid edges are sealed with clay smeared cloth wrapped in seven consecutive layer container is kept in a heap of paddy ( to maintain a constant temperature during fermentation process).
- 6. After a specified period of time the earthern lid is removed carefully and the content of vessel or examined to ascertain the process of fermentation is completed or not. Fluid is decanted strained kept as it for two or three days it is again a strain to mix sentiments properly and packed in bottom. Preparation: Asava (no decoction process ) Sugar jaggery honey is taken dissolved boiled and then cooled Transferred to the fermenting vessel herbs added as mentioned in the formula Container is covered with lid and edges are sealed with clay smeared cloth wrapped in seven consecutive layered place in a heap of paddy After a time it is checked that the fermentation process is completed or not then packed in bottle.
- 7. Procedure 1. Measure 25 ml of formulation by measuring cylinder and transfer to distillation flak having capacity of 500 ml. 2. Wash the measuring cylinder with 150 ml of water and add it to the flask. Add some porcelain pieces to the flask and distilled them. 3. Collect about 90 ml of distillate from this take 25 ml of distillate and dilute it to 100 ml with water and with the help of a specific gravity bottle determine the specific gravity of liquid at 25°C. 4. Follow the alcohol content table with specific gravity and determine the V/V alcohol content in the sample. 5. Calculate the % alcohol content by using the multiplication factor. Determine the Specific Gravity: A tube of known weight (W) was filled first with essential oil and then with water and the respective weight w1 and w2 was determined. Then, the specific gravity was calculated using the following formula: d = (w1-w)/(w2-w)
- 9. Calculation Weight of empty specific gravity bottle (w) = 21.12g Weight of water and RD bottle (w2) = 45.26g Weight of 25 ml alcohol and RD bottle (w1) = 45.79g d = (w1-w)/(w2-w) d = 45.79 – 21.12/ 45.26 – 21.12 d = 24.67/24.14 d = 1.021 = 2.7%
- 10. SKILL REQUIRED - Ash value is useful in determining authenticity and purity of sample and also these values are important qualitative standards. The total ash value, acid insoluble ash, water soluble ash was found to be 11.75%, 7.45% and 7.85%. This percentage clearly indicates that the root is best for drug action and effects.
- 11. PAPER CHROMATOGRAPHY - paper chromatography, in analytical chemistry, technique for separating dissolved chemical substances by taking advantage of their different rates of migration across sheets of paper.
- 12. THIN LAYER CHROMATOGRAPHY - is a chromatography technique used to separate non-volatile mixtures. Thin- layer chromatography is performed on a sheet of an inert substrate such as glass, plastic, or aluminium foil, which is coated with a thin layer of adsorbent material, usually silica gel, aluminium oxide, or cellulose.
- 13. COLUMN CHROMATOGRAPHY - The principle behind column chromatography is adsorption, in which a mixture of components dissolved in the mobile phase is introduced in to the column and the components move depending on their relative affinities.
- 14. REFERENCES FROM ARTICLES Lal, Uma & Tripathi, Shailendra & Jachak, Sanjay & Bhutani, Kamlesh & Singh, Inder Pal. (2009). HPLC Analysis and Standardization of Arjunarishta–An Ayurvedic Cardioprotective Formulation. Sci Pharm. 77. 605-616. 10.3797/scipharm.0906-03. Sayyad, S. F., et al. "Preparation and evaluation of fermented Ayurvedic formulation: Arjunarishta." Journal of Applied Pharmaceutical Science Issue (2012): 122-124.