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A RAPID TEST FOR FUNGUS THAT CAUSED
INJECTION DEATHS IS ANNOUNCED AND
BLOOD-BASED BIOMARKERS MAY LEAD TO
EARLIER DIAGNOSIS OF PARKINSON´S
DISEASE

MARIA CAMILA JARAMILLO MONSALVE
MEDCINE STUDENT

INTRODUCTION

Polymerase chain reaction
allows amplification of small
DNA fragments

Real time PCR is a useful method
for the detection and
quantification of infectious agents

A RAPID TEST FOR FUNGUS THAT
CAUSED INJECTION DEATHS IS
ANNOUNCED

Newswise. January 9 of 2013.
Source newsroom: University of
Medicine and Dentistry of New
Jersey (UMDNJ)

INJECTION DEATHS IS ANNOUNCED

Marketing of a contaminated
steroid medication by an
infectious fungus causes
some patients deaths.

The detection of this fungus
in biofluids is difficult,
because he tends not to be
free-floating in the samples.


The development of a
sensitive and effective essay
allows a rapid detection of
the fungus in samples.

The essay is very useful
to get an early
diagnostic.


The assay is based on the
use of molecular TEST FOR FUNGUS THAT CAUSED
A RAPID
beacon
technology in real time PCR. IS ANNOUNCED
INJECTION DEATHS

This is a fast method
to detect the fungus
and prevent
consequences

OBSERVATION
I think that the creation of specific
and immediate assay to detect the
presence of the infecting fungus can
decrease the consequences of a
mistake that could cost the lives of
many people, and provide an
effective way to create another
similar methods to detect infectious
diseases quickly to lower the rates of
morbimortality

BLOOD-BASED BIOMARKERS
MAY LEAD TO EARLIER
DIAGNOSIS OF PARKINSON´S
DISEASE
Science Daily

Sok Kean Khoo, David Petillo, Un
Jung Kang, James H. Resau, Brian
Berryhill , Jan Linder, Lars Forsgren,
Leslie A. Neuman, Aik Choon
Tan. Plasma-Based Circulating
MicroRNA Biomarkers for
Parkinson's Disease. Journal of
Parkinson's Disease, Volume 2/Issue 4
(December 2012) DOI: 10.3233/JPD-
012144

BLOOD-BASED BIOMARKERS MAY LEAD
TO EARLIER DIAGNOSIS OF PARKINSON´S
DISEASE

Parkinson´s disease is a
neurodegenerative
process.

The differential diagnostic is
based in the evaluation of motor
functions through a subjective
clinical rating scales.

DISEASE

The loss of dopaminergic
neurons causes motor
abnormalities, specific of
Parkinson´s disease.

That’s the reason why its
diagnosis take a lot of
time.

DISEASE

The researchers identified
and tested the first blood-
based circulating microRNA
biomarkers for PD.

OBSERVATION
I think it´s amazing how the
search for diagnostic methods
more specific and sensitive, they
can give a pertinent treatment
for PD patients and this way to
prevent motor and cognitive
irreversible consequences.

MEDICAL UTILITY

The new molecular
techniques to detect
infectious agents or
diseases allows an early
diagnostic.

MEDICAL UTILITY

This methods can
anticipate therapeutic
interventions and prevent
the fatal consequences.

MEDICAL UTILITY
The detection of
fungal infections in
drugs

An effective way to prevent
the sale of contaminated
medicaments.

MEDICAL UTILITY
Blood-based biomarkers pretends
improving the PD diagnostic to
prevent irreversible loss of motor
abilities

BIBLIOGRAPHY

[http://www.sciencedaily.com/releases/2013/01/1301201
45842.htm] checked on Juanary 7th of 2013.”Blood
Based Biomarkers May Lead to Earlier Diagnosis of
Parkinson's Disease”

[http://www.newswise.com/articles/a-rapid-test-for-
fungus-that-caused-injection-deaths-is-announced]
checked on January 6th of 2013. “A Rapid Test for
Fungus That Caused Injection Deaths Is Announced”

Martínez, Lina María; Vargas, Natalia ; Toro, Eduardo;
Pamplona, Ana P; Quevedo, Esteban O. “Biología
molecular”. Ed 7. 2012 . Pp 121

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