How to reformat pc
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Computers store data and operating instructions on hard disks. Formatting removes all data from these disks, which is often necessary due to virus infections or a full disk. The document provides step-by-step instructions to reformat a hard disk using a Windows XP CD, including backing up data, booting from the CD, deleting disk partitions, installing Windows to the unallocated space, and restoring backed-up data after completion.
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Spectrophotometer instrument basics -.pptxmuthulakshmitc A spectrophotometer is an essential analytical instrument widely used in various scientific disciplines, including chemistry, biology, physics, environmental science, clinical diagnostics, and materials science, for the quantitative analysis of substances based on their interaction with light. At its core, a spectrophotometer measures the amount of light that a chemical substance absorbs by determining the intensity of light as a beam of light passes through the sample solution. The fundamental principle behind the spectrophotometer is the Beer-Lambert law, which relates the absorption of light to the properties of the material through which the light is traveling. According to this law, the absorbance is directly proportional to the concentration of the absorbing species in the material and the path length that the light travels through the sample. By exploiting this principle, a spectrophotometer provides a powerful, non-destructive means of identifying and quantifying substances in both qualitative and quantitative studies.
The construction of a spectrophotometer involves several key components, each playing a vital role in the overall functioning of the instrument. The first critical component is the light source. The choice of the light source depends on the range of wavelengths needed for analysis. For ultraviolet (UV) light, typically a deuterium lamp is used, while tungsten filament lamps are commonly used for the visible light range. In some advanced spectrophotometers, xenon lamps or other broad-spectrum sources may be used to cover a wider range of wavelengths. The light emitted from the source is then directed toward a monochromator, which isolates the desired wavelength of light from the full spectrum emitted by the lamp. Monochromators generally consist of a prism or a diffraction grating, which disperses the light into its component wavelengths. By rotating the monochromator, the instrument can select and pass a narrow band of wavelengths to the sample, ensuring that only light of the desired wavelength reaches the sample compartment.
The sample is typically held in a cuvette, a small transparent container made of quartz, glass, or plastic, depending on the wavelength range of interest. Quartz cuvettes are used for UV measurements since they do not absorb UV light, while plastic or glass cuvettes are sufficient for visible light applications. The path length of the cuvette, usually 1 cm, is a critical parameter because it influences the absorbance readings according to the Beer-Lambert law. Once the monochromatic light passes through the sample, it emerges with reduced intensity due to absorption by the sample. The transmitted light is then collected by a photodetector, which converts the light signal into an electrical signal. This electrical signal is proportional to the intensity of the transmitted light and is processed by the instrument’s electronics to calculate absorbance or transmittance values. These values are then give
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pharmacology.pdffffffffffffffffffffffffffanooshaazam312 Pulmonary delivery of biologics (insulin, vaccines, mRNA)
Definition and Purpose
Pulmonary Delivery: Involves administering biologics directly to the lungs via inhalation.
Goal: To achieve rapid absorption into the bloodstream, enhance bioavailability, and improve therapeutic outcomes.
Types of Biologics
• Insulin: Used for diabetes management; inhaled insulin can provide a non-invasive alternative to injections.
• Vaccines: Pulmonary delivery of vaccines (e.g., mRNA vaccines) can stimulate local and systemic immune responses.
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Advantages
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Future Directions
• Personalized Medicine: Potential for tailored therapies based on individual patient needs and responses.
• Combination Therapies: Exploring the use of pulmonary delivery for combination therapies targeting multiple diseases.
Gene therapy via inhalation
Definition and Purpose
• Gene Therapy: A technique that involves introducing, removing, or altering genetic material within a patient’s cells to treat or prevent disease.
• Inhalation Delivery: Administering gene therapies directly to the lungs through inhalation, targeting respiratory diseases and conditions.
Mechanism of Action
• Aerosolized Vectors: Utilizes viral or non-viral vectors (e.g., liposomes, nanoparticles) to deliver therapeutic genes to lung cells.
• Cell Uptake: Once inhaled, the vectors penetrate the alveolar epithelium and deliver genetic material to target cells.
Advantages
• Localized Treatment: Direct delivery to the lungs can enhance therapeutic effects while minimizing systemic side effects.
• Non-Invasive: Inhalation is less invasive than traditional injection methods, improving patient compliance.
• Rapid Onset: Potential for quicker therapeutic effects due to direct absorption in the pulmonary system.
Personalized inhaler systems with sensors
• Smart Inhalers: Devices with sensors that track usage and technique.
• Real-Time Monitoring: Connect to apps for data on adherence and inhalation patterns.
• Tailored Treatment: Adjusts medication based on individual usage data.
• Patient Engagement: Provides feedback and reminders to empower self-management.
• Improved Outcomes: Enhances adherence and reduces exacerbations in respiratory conditions.
• Future Potential: May integrate with other health data and use AI for predictive insights.
Sustained-Release Nano Formulations
Definition: Nanoscale drug delivery systems that release therapeutic agents over an extended period.
Components: Made from polymers, lipids, or inorganic materials that encapsulate drugs.
Mechanism:
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- 2. Computers store their data and operating procedures on devices called Hard Disks. The process of removing all data from these disks is called (re)formatting. More often than most would like a computer's hard disk must be wiped clean, whether because a virus infection, or the disk may just be full.
- 3. 1. Back up your data. All important data should be backed up before starting this procedure. Remember that all hard disk data will be lost when you reformat..
- 5. 2. Insert the Windows XP CD-ROM or DVD-ROM into your computer.
- 7. 3. Restart the PC.
- 9. 4. Press any key. Soon after the power on self test (POST) a message similar to "Press any key to boot from CD" will appear. Press any key at this point.
- 11. 5. Press the F8 key to agree to the Microsoft end user license agreement when prompted to do so.
- 13. 6. When the prompt showing available space is shown select each field that does not say "Unallocated Space".
- 15. 7.Press d (for delete) followed by L (no need to capitalize) to confirm partition deletion.
- 17. 8. Repeat steps 6 and 7 until the only field left is "Unallocated Space"
- 19. 9. Press enter to install windows to the unallocated space, select Quick Format instead of standard. If you're reformatting to recover from error, you will want to do a Full Format otherwise your error may still exist.
- 20. 10. The PC should restart, then select your language and local preferences when prompted to do so.
- 22. 11. When the administrator password prompt comes up enter the desired password.
- 24. 12. All done, restore the documents you backed up before starting this procedure and re-install your applications.
- 26. Thank you!