Hypermobile Ehlers-Danlos Syndrome (hEDS) is a genetic connective tissue disorder affecting an estimated 1 in 5,000 people, characterized by fragile and stretchy collagen leading to joint hypermobility and a range of associated symptoms. Diagnosis relies on clinical criteria as no genetic test is available, and recent classifications identify a spectrum from hypermobility to hEDS and Hypermobile Spectrum Disorders (HSD). Management emphasizes avoiding high-risk activities, maintaining joint health, and the importance of early intervention for related complications.