University campuses serve as critical infrastructures within specific regions, playing a pivotal role in the development of surrounding communities by fostering knowledge dissemination and contributing to the establishment of knowledge clusters. This study explores the impact of Istanbul Gelisim University’s sustainability initiatives, focusing on student engagement, strategic planning, collaboration, and innovation as key drivers of urban sustainability. The study proposes an integrated framework combining current practices with innovative, actionable steps to guide sustainable campus development. Emphasising alignment with the UN Sustainable Development Goals (SDGs), the study highlights the university’s role in minimising environmental impact and promoting inclusive stakeholder participation.