The document discusses 7 strategies for enterprises to survive disruptions from the nexus of forces in 21st century IT, including big data, cloud computing, mobile technology, and social media. These strategies are: 1) addressing big data challenges through improved information management and analytics, 2) adopting in-memory computing to improve data velocity, 3) embracing cloud computing while securing corporate data, 4) developing hybrid IT approaches using private and public clouds, 5) managing challenges from the growing Internet of Things, 6) achieving full integration across new IT deployments, and 7) leveraging platforms that integrate solutions to simplify operations.