Lumbarization and sacralization are spinal anomalies where the typical number of vertebrae in the lumbar or sacral spine is altered. Lumbarization occurs when the first sacral segment is not fully fused, appearing as a sixth lumbar vertebra. Sacralization is when the fifth lumbar vertebra is fused to the sacrum, appearing as one fewer lumbar vertebra. These conditions can cause lower back pain and biomechanical strain. Treatment may include medications, injections, physiotherapy including stretching, strengthening, and stabilization exercises, and in some cases surgery.