Wildcard and SAN certificates both allow securing multiple domains or subdomains with a single certificate. Wildcard certificates use a wildcard character to secure any subdomain of a domain, while SAN certificates explicitly list each domain or subdomain. Wildcard certificates have an advantage in management simplicity but less security, while SAN certificates offer more security but require updating if domains change. The document provides a comparison of features between wildcard and SAN certificates to help determine the best type.