This document summarizes a presentation about preventing and resolving MySQL downtime. It discusses common issues that can cause downtime like disk failures, crashes from bugs or upgrades, unnoticed cluster node failures, and performance problems. Solutions presented include tools from Percona like XtraDB Cluster for high availability, the Percona Monitoring Plugins, and the Percona Toolkit. The presentation also covers preventing issues through monitoring, proper configuration of MySQL, the operating system, and hardware.