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IDENTIFICATION OF DIABETIC
RETINOPATHY USING THE RETINAL
IMAGES
Department of ECE
-by
M.Ayisha sithika
M.Basima banu
K.Gayathri
Batch number :111
Under the supervision of
Miss L.C.MEENA(Asst.PROFESSOR) ,DACE
1
AIM
 To identify diabetic retinopathy using the retinal images in an
efficient manner.
 Exudates is one of the features used to identify the diabetic
retinopathy .
OBJECTIVE
 Exudates ,a very important and mostly occurring feature of
retinopathy is identified using k-means and naives bayes classifier.
2
INTRODUCTION-EYE
INTRODUCTION-DIABETIC
RETINOPAHTY
DIABETIC RETINOPATHY
• DR is an eye disease which has been caused due to high blood
sugar level.
TYPES OF DR
1) Non-proliferative diabetic retinopathy
2) Diabetic maculopathy
3) Proliferative diabetic retinopathy
Normal Defective
EXUDATES
• Primary sign of diabetic retinopathy
• It is lipids and proteins leaks from damaged
blood vessels.
FUNDUS IMAGE OF EYE
• FUNDUS OF EYE: The back portion of the interior of the
eyeball, visible through the pupil by use of the ophthalmoscope.
• FUNDUS IMAGE: Fundus photography is performed by a
fundus camera, which basically consists of a specialized low
power microscope with an attached camera.
6
LITREATURE SURVEY
1.Akara Sopharak , Bunyarit Uyyanonvara and Sarah Barman[6],
“Automatic Exudate Detection from Non-dilated Diabetic
Retinopathy-Retinal Images Using Fuzzy C-means Clustering”.
ADVANTAGES:
 The low contrast retinal image- intensity increased and a
number of edge pixels were extracted.
DISADVANTAGES:
 More time consuming.
—
7
2.T. Walter, J. Klein, P. Massin, and A. Erginary[2],“A
contribution of image processing to the diagnosis of
diabetic retinopathy thy,detection of exudates in colour
fundus images of the human retina".
ADVANTAGES:
 Time consumption is reduced as it uses mathematical
morphology techniques .
DISADVANTAGES:
 The paper ignored some types of errors on the border
of the segmented exudates in their reported performances.
 Time consumption is reduced but not to great extent. 8
NOVELTY USED
• In our project we are using k-means clustering algorithm with
naive bayes classifier.
• Fuzzy c-means algorithm, as consumes time, so k-means is
used to reduce time.
• Naive bayes,a type of classifier is used to increase the
accuracy and sensitivity of the detection.
9
WORK ACCOMPLISHED
BLOCK DIAGRAM:
INPUT
RETINAL
IMAGE
PRE-
PROCESSING
SEGMENTATION
FEATURE
EXTRACTION
CLASSIFICATION
EXUDATES
NON-
EXUDATES
STEP 1:PRE-PROCESSING
RGB to HIS
image
Median
filtering
CLAHE
HSI to RGB
image
STEP 2:IMAGE SEGMENTATION
RGB to
l*a*b colour
space
a*b alone
using k-means
clustering
five clusters
labels every
pixel
Colour
segmented
images
optic disc is
localized
STEP 3:FEATURE EXTRACTION
• On the basis of colour and texture orientation,
features are extracted using GLCM.
STEP 4: CLASSIFICATION
• The final step is classification of given input as
exudates (or) non-exudates by naive bayes
classifier.
PRE-PROCESSED OUTPUT
Input retinal image
H component S Component I Component
HSI Components
Filtered I component CLAHE image Pre-processed image
SEGMENTATION OUTPUT
Image Labeled By Cluster Index
a. L channel b. A channel c. B channel
LAB colour space images
CLUSTER FORMATION
cluster1 cluster2 cluster3
cluster4 cluster5
Cluster Output
EXECUTION OF FINAL OUTPUT
CONCLUSION
• The selected features clustered by k-means clustering and
classified into exudates and non –exudates using naive bayes
classifier.
• Using this approach, the exudates are detected with 98%
success rate.
FUTURE WORK
• Detection of Micro-aneurysm and also maculopathy be
predicted and performance can be compared.
REFERENCES
[1] Wynne Hsu, P M D S Pallawala, Mong Li Lee, KahGuan Au Eong(2001),”The Role
of Domain Knowledge in the Detection of Retinal Hard Exudates”, IEEE
Conference on Computer Vision and Pattern Recognition (CVPR), Kauai Marriott,
Hawaii, vol.12,pp. 533-548.
[2] T. Walter, J.Klein, P.Massin and A.Erginary(2002), “A Contribution of image
processing to the diagnosis of Diabetic Retinopathy detection of exudates in color
fundus images of the human retina”, IEEE Trans. On Med. images, vol. 21, no. 10,
pp. 1236-1243.
[3] Pizer. S.M(2003),“The Medical Image Display and analysis group at the university
of North Carolina:Reminiscences and philosophy ”, IEEE Trans On Medical
Imaging, vol. 22, no. 1, pp. 2-10.
[4] Fleming. AD, Philips. S, Goatman. KA, Williams. GJ, Olson.JA, sharp.
PF(2007),“Automated detection of exudates for Diabetic Retinopathy Screening”,
Journal of Phys. Med. Bio., vol. 52, no. 24, pp. 7385-7396.
[5]Alireza Osareh, Bita Shadgar, and Richard Markham(2009), “A Computational-
Intelligence-Based Approach for Detection of Exudates in Diabetic Retinopathy
Images”,IEEE Transactions on Information Technology in Biomedicine,vol. 13, no.
4,pp.535-545.International Diabetic Federation (IDF), 2009a, Latest diabetes
figures paint grim global picture.
• [6] Akara Sopharak, Bunyarit Uyyanonvara, Sarah Barman(2009), “Automatic Exudate
Detection from Non-dilated Diabetic Retinopathy retinal images using Fuzzy Cleans
Clustering” Journal of Sensors, vol.9, No. 3, pp 2148- 2161.
• [7] Saiprasad Ravishankar, Arpit Jain, Anurag Mittal(2009),“Automated feature extraction for
early detection of Diabetic Retinopathy in fundus images”,IEEE Conference on Computer
vision and pattern Recognition, pp. 210-217.
• [8] Doaa Youssef, Nahed Solouma, Amr El-dib, Mai Mabrouk(2010),“New Feature-Based
Detection of Blood Vessels and Exudates in Color Fundus Images” IEEE conference on Image
Processing Theory, Tools and Applications, vol.16,pp.294-299
• [9] Guoliang Fang, Nan Yang, Huchuan Lu and Kaisong Li(2010),“Automatic Segmentation
of Hard Exudates in fundus images based on Boosted Soft Segmentation”, International
Conference on Intelligent Control and Information Processing, vol.13,pp. 633-638.
• [10] Plissiti.M.E., Nikar.C, Charchanti.A(2011),“Automated detection of cell nuclei in pap
smear images using morphological reconstruction and clustering” IEEE Trans. On
Insformation Technology in Biomedicine, vol. 2, pp. 233-241.
PROJECT FINAL PPT
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PROJECT FINAL PPT

  • 1. IDENTIFICATION OF DIABETIC RETINOPATHY USING THE RETINAL IMAGES Department of ECE -by M.Ayisha sithika M.Basima banu K.Gayathri Batch number :111 Under the supervision of Miss L.C.MEENA(Asst.PROFESSOR) ,DACE 1
  • 2. AIM  To identify diabetic retinopathy using the retinal images in an efficient manner.  Exudates is one of the features used to identify the diabetic retinopathy . OBJECTIVE  Exudates ,a very important and mostly occurring feature of retinopathy is identified using k-means and naives bayes classifier. 2
  • 4. INTRODUCTION-DIABETIC RETINOPAHTY DIABETIC RETINOPATHY • DR is an eye disease which has been caused due to high blood sugar level. TYPES OF DR 1) Non-proliferative diabetic retinopathy 2) Diabetic maculopathy 3) Proliferative diabetic retinopathy
  • 6. EXUDATES • Primary sign of diabetic retinopathy • It is lipids and proteins leaks from damaged blood vessels. FUNDUS IMAGE OF EYE • FUNDUS OF EYE: The back portion of the interior of the eyeball, visible through the pupil by use of the ophthalmoscope. • FUNDUS IMAGE: Fundus photography is performed by a fundus camera, which basically consists of a specialized low power microscope with an attached camera. 6
  • 7. LITREATURE SURVEY 1.Akara Sopharak , Bunyarit Uyyanonvara and Sarah Barman[6], “Automatic Exudate Detection from Non-dilated Diabetic Retinopathy-Retinal Images Using Fuzzy C-means Clustering”. ADVANTAGES:  The low contrast retinal image- intensity increased and a number of edge pixels were extracted. DISADVANTAGES:  More time consuming. — 7
  • 8. 2.T. Walter, J. Klein, P. Massin, and A. Erginary[2],“A contribution of image processing to the diagnosis of diabetic retinopathy thy,detection of exudates in colour fundus images of the human retina". ADVANTAGES:  Time consumption is reduced as it uses mathematical morphology techniques . DISADVANTAGES:  The paper ignored some types of errors on the border of the segmented exudates in their reported performances.  Time consumption is reduced but not to great extent. 8
  • 9. NOVELTY USED • In our project we are using k-means clustering algorithm with naive bayes classifier. • Fuzzy c-means algorithm, as consumes time, so k-means is used to reduce time. • Naive bayes,a type of classifier is used to increase the accuracy and sensitivity of the detection. 9
  • 11. STEP 1:PRE-PROCESSING RGB to HIS image Median filtering CLAHE HSI to RGB image
  • 12. STEP 2:IMAGE SEGMENTATION RGB to l*a*b colour space a*b alone using k-means clustering five clusters labels every pixel Colour segmented images optic disc is localized
  • 13. STEP 3:FEATURE EXTRACTION • On the basis of colour and texture orientation, features are extracted using GLCM. STEP 4: CLASSIFICATION • The final step is classification of given input as exudates (or) non-exudates by naive bayes classifier.
  • 14. PRE-PROCESSED OUTPUT Input retinal image H component S Component I Component HSI Components
  • 15. Filtered I component CLAHE image Pre-processed image
  • 16. SEGMENTATION OUTPUT Image Labeled By Cluster Index a. L channel b. A channel c. B channel LAB colour space images
  • 17. CLUSTER FORMATION cluster1 cluster2 cluster3 cluster4 cluster5 Cluster Output
  • 19. CONCLUSION • The selected features clustered by k-means clustering and classified into exudates and non –exudates using naive bayes classifier. • Using this approach, the exudates are detected with 98% success rate. FUTURE WORK • Detection of Micro-aneurysm and also maculopathy be predicted and performance can be compared.
  • 20. REFERENCES [1] Wynne Hsu, P M D S Pallawala, Mong Li Lee, KahGuan Au Eong(2001),”The Role of Domain Knowledge in the Detection of Retinal Hard Exudates”, IEEE Conference on Computer Vision and Pattern Recognition (CVPR), Kauai Marriott, Hawaii, vol.12,pp. 533-548. [2] T. Walter, J.Klein, P.Massin and A.Erginary(2002), “A Contribution of image processing to the diagnosis of Diabetic Retinopathy detection of exudates in color fundus images of the human retina”, IEEE Trans. On Med. images, vol. 21, no. 10, pp. 1236-1243. [3] Pizer. S.M(2003),“The Medical Image Display and analysis group at the university of North Carolina:Reminiscences and philosophy ”, IEEE Trans On Medical Imaging, vol. 22, no. 1, pp. 2-10. [4] Fleming. AD, Philips. S, Goatman. KA, Williams. GJ, Olson.JA, sharp. PF(2007),“Automated detection of exudates for Diabetic Retinopathy Screening”, Journal of Phys. Med. Bio., vol. 52, no. 24, pp. 7385-7396. [5]Alireza Osareh, Bita Shadgar, and Richard Markham(2009), “A Computational- Intelligence-Based Approach for Detection of Exudates in Diabetic Retinopathy Images”,IEEE Transactions on Information Technology in Biomedicine,vol. 13, no. 4,pp.535-545.International Diabetic Federation (IDF), 2009a, Latest diabetes figures paint grim global picture.
  • 21. • [6] Akara Sopharak, Bunyarit Uyyanonvara, Sarah Barman(2009), “Automatic Exudate Detection from Non-dilated Diabetic Retinopathy retinal images using Fuzzy Cleans Clustering” Journal of Sensors, vol.9, No. 3, pp 2148- 2161. • [7] Saiprasad Ravishankar, Arpit Jain, Anurag Mittal(2009),“Automated feature extraction for early detection of Diabetic Retinopathy in fundus images”,IEEE Conference on Computer vision and pattern Recognition, pp. 210-217. • [8] Doaa Youssef, Nahed Solouma, Amr El-dib, Mai Mabrouk(2010),“New Feature-Based Detection of Blood Vessels and Exudates in Color Fundus Images” IEEE conference on Image Processing Theory, Tools and Applications, vol.16,pp.294-299 • [9] Guoliang Fang, Nan Yang, Huchuan Lu and Kaisong Li(2010),“Automatic Segmentation of Hard Exudates in fundus images based on Boosted Soft Segmentation”, International Conference on Intelligent Control and Information Processing, vol.13,pp. 633-638. • [10] Plissiti.M.E., Nikar.C, Charchanti.A(2011),“Automated detection of cell nuclei in pap smear images using morphological reconstruction and clustering” IEEE Trans. On Insformation Technology in Biomedicine, vol. 2, pp. 233-241.