This document provides tips and best practices for optimizing PHP application performance when using Nginx as a web server. It discusses running PHP with PHP-FPM as a FastCGI process manager instead of using the Apache module. Key points covered include configuring Nginx and PHP-FPM to communicate via sockets, using Nginx caching and rewriting URLs to route requests to PHP scripts. Benchmark results show Nginx outperforming Apache for static and dynamic content.