Scope of Pharmaceutical Microbiology
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The document discusses the extensive role of microbiology in pharmaceutical sciences, highlighting its applications across various sectors including medical devices, biopharmaceutical testing, and the production of vaccines and antibiotics. It emphasizes the importance of understanding microbiological principles for ensuring product safety and efficacy while preventing contamination. Additionally, it covers the significance of microbial control in the production of cosmaceuticals and the necessity of collaboration among professionals to enhance drug therapies and health practices.
Scope of Pharmaceutical Microbiology
- 1. SCOPE OF MICROBIOLOGY WITH SPECIAL REFERENCE TO PHARMACEUTICAL SCIENCES Atifa Ambreen M. Phil, Microbiology Government College University, Faisalabad
- 2. SCOPE OF PHARMACEUTICAL MICROBIOLOGY The scope of microbiology is to immense due to its ability to control all critical points of many fields like Medical, Dairy, Pharmaceutical, Industrial, Clinical, Research, water industry, agriculture, nanotechnology and chemical etc.
- 3. APPLICATION OF MICROBIOLOGY IN VARIOUS SECTORS Pharma industries Medical devices Biopharmaceutical testing Cosmaceuticals Cells banks Viral seeds Fermentation models Pollution and environmental microbiology
- 4. PHARMA INDUSTRIES AND RESEARCH CENTERS Understanding the principle of microbiology, cell structure and functions of microbes and human cell mechanism allows pharmacists to discover antimicrobial drugs that would prevent an escalating number of communicable diseases. Pharmaceutical microbiologist work synergistically with others to ensure that drug therapies target opportunistic microbes (e.g. fungi) without harming its host.
- 5. Another important role of pharmaceuticals is the microbes for the medically important studies such as bacteriorhodopsin – adapted from a protein for the plasma membrane of Halobacterium salinarum.
- 6. PHARMA IDUSTRIES Production of antibiotics, enzymes, vaccines, vitamins and other pharmaceutical products. Concept of manufacturing, preventing drug or drug product by microbial contamination. Virus are used for preparation of vaccines that have great impact on the community by preventing from deadly diseases e.g. Measles, chicken pox, hepatitis, tuberculosis, polio. Edward Jenner’s successful cowpox vaccine (in 1798)
- 7. Bacterial vaccines: Pneumonia (Streptococcus pneumoniae) Two vaccines are available: pneumococcal polysaccharide and pneumococcal polysaccharide- protein conjugate vaccines.
- 8. MEDICAL DEVICES Studying microbiology helps in understanding mechanism/principle of medical devices such as fluorescent fusion, which are used for fast and precise detection of pathogens in tissue samples. It is a technology for carrying out immunofluorescence studies that may be applied to find specific cells in complex biological system.
- 9. COSMACEUTICALS Microbial contamination of cosmetic products is a matter of great importance to the industry and it can become a major cause of both product and economic losses. The water and nutrients present in cosmetics make the susceptible to microbial growth, although only a few cases of human injury due to contaminated cosmetics have been reported.
- 10. Therefore, studying microbiology is necessary for preparation, processing and quality control of cosmaceuticals.
- 11. BIOPHARMACEUTICAL TESTING A biopharmaceutical, also known as a biological medical product, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semi synthesized from biological sources. They can be used in both human and animal medicine.
- 12. Biopharmaceutical are a class of medical products which are typically produced using biotechnology, most commonly in a bioreactor. These include: therapeutic proteins, vaccines, oligonucleotides etc. The production of these molecules is a complex and sensitive to contaminations.
- 13. Mycoplasma, viruses, bacteria and fungi can cause trouble, even in well maintained and well designed productions plants. When microbes are used for their beneficial effects, it is equally necessary to eradicate them when needed e.g. from sterile products, hospital sectors to regulate good health practices.
- 14. CELL BANKS A cell banks refers to the facility that stores cells of specific genome for the purpose of future use in a products or medicine needs.
- 15. The advantages of cell banks are: A. Detailed characterization of the cell line. B. Decrease in the likelihood. C. An increase in the detection of cross- contamination of the cell line. Services of pharmacist are required in analysis and quality control section.
- 16. FERMENTATION MODELS Humans have unknowingly made use of microorganisms for centuries to carry out fermentation processes to make yoghurt, cheese, bread, wine and beer etc. Besides classifying fermentation processes as batch, fed- batch or continuous they can be classified according to how dependent the product formation is upon energy consumption.
- 17. SOME EXAMPLES OF FERMENTATION PRODUCTS