Internet is the boon in modern era as every organization uses it for dissemination of information and ecommerce
related applications. Sometimes people of organization feel delay while accessing internet in
spite of proper bandwidth. Prediction model of web caching and prefetching is an ideal solution of this
delay problem. Prediction model analysing history of internet user from server raw log files and determine
future sequence of web objects and placed all web objects to nearer to the user so access latency could be
reduced to some extent and problem of delay is to be solved. To determine sequence of future web objects,
it is necessary to determine proximity of one web object with other by identifying proper distance metric
technique related to web caching and prefetching. This paper studies different distance metric techniques
and concludes that bio informatics based distance metric techniques are ideal in context to Web Caching
and Web Prefetching