Noli Me Tangere, the first novel by Dr. José Rizal, follows a young Filipino man, Crisostomo Ibarra, who returns from Europe to confront the injustices in the Philippines. The novel, completed in 1887 and published with the assistance of Dr. Maximo Viola, features key characters representing various societal issues, including Maria Clara and the antagonistic friar Padre Damaso. Inspired by works like Uncle Tom's Cabin, Rizal uses the phrase 'noli me tangere' to explore the plight and awakening of Filipinos under colonial rule.