TJ Hughes, HPSU Industrial & Life Sciences Enterprise Ireland
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This document discusses Enterprise Ireland and the medical technologies sector. It notes that Enterprise Ireland works with Irish and foreign companies across the economy, including high potential startups, established SMEs, and multinationals. The medical technologies sector includes 250 clients focused on medical devices and technologies, generating over €1 billion in annual sales and employing 6,000 people in Ireland. The document outlines key areas and global markets for medical technologies and notes that emerging markets like China, India, Brazil and Mexico are growing fast, while the US, Western Europe and Japan currently dominate the global market.
![Projects we invest in
Eligible
Manufacture or internationally tradable service
Management control in Ireland
High Potential
Usually based on technological innovation
Export oriented
10 employees within 3/4 yrs, Sales > €1m [but life-
science is different!]](https://image.slidesharecdn.com/tjhmedtechideagen-120926061458-phpapp02/85/TJ-Hughes-HPSU-Industrial-Life-Sciences-Enterprise-Ireland-14-320.jpg)
![HPSU Investment
Due Diligence - the Business Plan
• Market Risks
• Execution Risks
• Financial Risks
Level of EI funding depends on exports, jobs &
cash need
EI Investment is in equity [CCRPs]
Minimum of matching external funding
Average initial investment €250k](https://image.slidesharecdn.com/tjhmedtechideagen-120926061458-phpapp02/85/TJ-Hughes-HPSU-Industrial-Life-Sciences-Enterprise-Ireland-15-320.jpg)
TJ Hughes, HPSU Industrial & Life Sciences Enterprise Ireland
- 1. Ideagen TJ Hughes HPSU 18th September 2012 Medical Technologies Sector
- 2. Enterprise Ireland works with… ….Internationally Trading A Large nd ID Companies Businesses throughout a (Exporting) the economy el Ir e Exporting SME’s is (HPSU’s) prr te En s B CE Micro Enterprises Domestic Market Businesses Large SME’s Micro Companies Businesses
- 3. Who we work with… High Potential Established Multinationals Start-up’s SME’s Entrepreneurs Manufacturing & starting companies Internationally Irish-based with an ability to Traded services food and natural compete in world resource companies that are companies markets employing overseas owned or ten or more controlled Potential Research Scaling Exporters Community Ambitious co’s Established SME’s Developing links with Irish with the ability to currently focussed on enterprise, MNCs to support scale & achieve the domestic market research collaboration, significant who have the ambition commercialisation of publicly success to export funded research, and access to FP7, ESA
- 5. It’s about Jobs and Economic Impact IRISH OWNED COMPANIES FOREIGN OWNED COMPANIES EMPLOYMENT = 145,983 EMPLOYMENT = 138,488 SPEND IN ECONOMY = €17.0bn SPEND IN ECONOMY = €17.9bn IRISH GOODS €2.2bn PAYROLL PAYROLL €5.4bn IRISH €7.6bn GOODS €7.7bn IRISH SERVICES IRISH €8.2bn SERVICES €3.9bn Source: 2010 ABSEI, 2011 Forfás Employment Survey 100,000 Jobs by 2016
- 6. Indigenous Life Sciences • 250 Clients – 50% Medical Technologies • 20 new start-ups per year / MBO’s • Medical sub-supply, finished devices (e.g., cardio-, peripheral, orthopaedics, NOTES), diagnostics, specialist services, connected health • €1bn+ Sales, Exports €760m, Employment of 6,000 people • 9% export growth in 2011 & 8% employment growth
- 7. Top 15 EU employment centres for Region medical devices Medical Devices European Share Employment Veneto, IT 21,269 4.32% Ireland, IE 20,360 4.13% Freiburg, DE 15,526 3.15% Lombardia, IT 15,005 3.05% Île de France, FR 11,158 2.27% Niedersachsen, DE 10,289 2.09% Emilia-Romagna, IT 9,860 2.00% Rhône-Alpes, FR 9,252 1.88% Figures for Karlsruhe, DE 8,565 1.74% 2007 Oberbayern, DE 8,061 1.64% Danmark, DK 7,948 1.61% Tübingen, DE 7,740 1.57% Stuttgart, DE 7,614 1.55% Espace Mittelland, CH 7,155 1.45% Berlin, DE 7,133 1.45%
- 8. Evolution of Medical Technologies 1980’s 1990’s 2020 • Silk & catgut suture • Dynamic monitoring 2 • E-Everything • Latex gloves • Titanium prosthetics • 0 Integrated Connected Health • Heavy Medical Equipment (beds) • Pulse oximetry Networks • Mechanical Respirators • Dissolving sutures 0 • Hospital to Home • Anaesthetic machines • Non latex gloves • 0 Regenerative Scaffolds & Stem • Cells Molecular diagnostics s • New Materials • D • BioDevices ru • Next generation g • Bespoke Biomedical Solutions el • ut Virtual Robotic Surgery in g st e nt s Design, Development, Prototyping, Commercialisation, Manufacturing, • Supply H Chain, Services y br id pr Servicisation of Drug & Device Industry!!! o st Prevention/Wellness/Compliance h Healthcare Intelligence – Data Management / Data Analytics et ic s • M in i m al ly
- 9. Medical technologies where to start Aesthetics/Dermatology (108 emerging companies) • Biomaterials (298 emerging companies) • Biotechnology/Cell Therapy (304 emerging companies) • Cardiovascular (416 emerging companies) • Dental (52 emerging companies) • Diagnostics (367 emerging companies) • Drug Delivery (179 emerging companies) • Endocrine (160 emerging companies) • Gastroenterology (139 emerging companies) • Gynecology/Women's Health (142 emerging companies) • Imaging (203 emerging companies) • Neurology (254 emerging companies) • Oncology (283 emerging companies) • Ophthalmology (117 emerging companies) • Orthopedics (302 emerging companies) • Pain Management (83 emerging companies) • Patient Management/Monitoring (278 emerging companies) • Respiratory (139 emerging companies) • Spine (234 emerging companies) • Surgery (241 emerging companies) • Urology (158 emerging companies) • Vascular (240 emerging companies) • Wound Management (111 emerging companies) Source Life Science Intelligence
- 10. Global market dominated by USA, Western Europe and Japan but Emerging markets growing fast china, India, Brazil, Mexico •Drivers • Restraints •Patient Demographics •Regulatory •Care models focussed on •Complex Purchasing systems wellness and prevention •Reimbursement cuts and cost •Tele-health or connected containment health • Challenges • Opportunity •Escalating costs •New innovations that give better clinical outcomes and improved •End to end disease quality of life management is inefficient •Regulatory •Efficiency improvements •Investment
- 11. Pharma & Medtech models globally are under strain, therefore Ireland INC also has a problem 11
- 12. Some hot areas • Transcather valves • Interventional treatment of Hypertension • Pulmonary Interventional tools • Regenerative medicine/organ replacement • Neuromodulation • Home dialysis • Robotics • Bioabsorable stents • Bionics • Non invasive body sculpting Source Frost and Sullivan
- 13. EI has significant funds Client company approvals 2011 = €110m+ Similar level of support in 2012 Approx 1/3 of funding towards Start-ups = €35m Support for Third Level is Separate 13
- 14. Projects we invest in Eligible Manufacture or internationally tradable service Management control in Ireland High Potential Usually based on technological innovation Export oriented 10 employees within 3/4 yrs, Sales > €1m [but life- science is different!]
- 15. HPSU Investment Due Diligence - the Business Plan • Market Risks • Execution Risks • Financial Risks Level of EI funding depends on exports, jobs & cash need EI Investment is in equity [CCRPs] Minimum of matching external funding Average initial investment €250k
- 16. Funding Pre-Seed Seed Funds €124 million VC Funds €520 million
- 17. Development Process BC A B A C A BC B A C Stakeholder Engagement Vital ABC & patients, regulatory bodies, Ethics Committees
- 18. Thank you
Editor's Notes
- #7: Also large multinational presence. Home to 9 of the worlds top 10 medical technologies companies (or 16 out of the top 25). Johnson and Johnson, General Electric, Medtronic, Fresenius, Siemens, Philips, Boston Scientific (5 facilities), Covidien (5), Stryker (3), Zimmer, Abbott Diabetes, Abbott Diagnostics, Abbott Vascular, Baxter (2) Bausch & Lomb etc. Large cluster in Galway region which is known internationally.