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Role of Transrectal Ultrasound (TRUS) in Male Infertility Dr. Ho Siew Hong Consultant Urologist S H Ho Urology and Laparoscopy Centre Gleneagles Hospital
What is TRUS ? Ultrasound probe placed within rectum 7 MHz frequency, higher frequency, shorter penetration, better resolution Complete picture of prostate, seminal vesicles and ejaculatory duct in real-time, by moving a few millimeters on transverse or longitudinal plane
TRUS
TRUS Sagital Transverse 135 Degrees
Role of TRUS in male infertility Evaluation of abnormalities of ejaculatory duct apparatus Able to determine level of obstruction in ejaculatory duct, aids in planning surgery Ultrasound guided aspiration – cyst, seminal vesicle fluid Almost replaced vasography in evaluation of ejaculatory duct obstruction Vasography still necessary if classical characteristics not present on TRUS
Anatomy of ejaculatory duct 3 parts of ejaculatory duct: Long, extra-prostatic Middle, intra-prostatic Distal, joining verumontanum in urethra Ejaculatory duct obstruction may be present in 5% of subfertile men
Indications for TRUS in  infertile males L ow ejaculate volume Z ero  (azoospermia)  or a decreased  (oligospermia)  number of sperm in the ejaculate S ignific a nt sperm motility abnormalities H istory of prostate infections, prostatitis
Clinical suspicion of diagnosis of ejaculatory duct obstruction Azoospermia Hematospermia Painful ejaculation Perineal pain Urinary tract infections or trauma
Causes of ejaculatory duct obstruction Seminal vesicle stones Mullerian duct (utricular) cysts Wolffian duct (diverticular) cysts Post-surgical scar tissue Post-inflammatory scar tissue Calcification  (stone)  near the verumontanum Congenital atresia Functional obstruction (alpha blocker, anti-psychotic, anti-depressants)
Diagnosis of ejaculatory duct obstruction Azoospermia E jaculate volume <2.0 ml and a pH<7.2 that contains no sperm or fructose. Normal serum FSH and testosterone. Testicular of normal size (20cc) and consistency.
TRUS diagnosis of ejaculatory duct obstruction D ilated seminal vesicles (>1.5 cm   width) D ilated ejaculatory ducts (>2.3 mm)  C yst, calcification or   stones along the duct TRUS and seminal vesicle aspiration showing the presence of sperm in the   seminal vesicle fluid within 2 days of ejaculation
Technique Left lateral position DRE Introduction of rectal ultrasound probe No anaesthesia required Mild sedation for drainage or aspiration
Transverse plane Prostate evaluation Base to apex Emphasis on base and mid prostate Seminal vesicle Small amount of urine in bladder is helpful
Prostate Bladder
 
 
 
Ejaculatory duct
Prostatic cyst,  infartion
Sagittal Plane Bladder neck Urethra Verumontanum Ejaculatory duct Seminal vesicles, one at a time
 
Urethra
Ejaculatory duct
D ilated ejaculatory ducts (>2.3 mm)
D ilated seminal vesicles (>1.5 cm   width)
Aspiration from  seminal vesicles or cysts Negative urine culture Mild sedation - midazolam Prophylactic antibiotics  - 6 to 24 hours prior to aspiration e.g. ciprofloxacillin 500 mg - i/v gentamicin 160 mg before aspiration Continue oral antibiotics for another 3-5 days
TRUS aspiration of  utricular  cyst
TRUS – ejaculatory duct obstruction
Conclusions TRUS is the ideal instrument for evaluation of ejaculatory duct disorders Fast replacing vasography Excellent planning for surgery Option of aspiration from seminal vesicle (diagnostic) or urticle cyst (therapeutic)
Thank you

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TRUS in Evaluation of Male Infertility

  • 1. Role of Transrectal Ultrasound (TRUS) in Male Infertility Dr. Ho Siew Hong Consultant Urologist S H Ho Urology and Laparoscopy Centre Gleneagles Hospital
  • 2. What is TRUS ? Ultrasound probe placed within rectum 7 MHz frequency, higher frequency, shorter penetration, better resolution Complete picture of prostate, seminal vesicles and ejaculatory duct in real-time, by moving a few millimeters on transverse or longitudinal plane
  • 5. Role of TRUS in male infertility Evaluation of abnormalities of ejaculatory duct apparatus Able to determine level of obstruction in ejaculatory duct, aids in planning surgery Ultrasound guided aspiration – cyst, seminal vesicle fluid Almost replaced vasography in evaluation of ejaculatory duct obstruction Vasography still necessary if classical characteristics not present on TRUS
  • 6. Anatomy of ejaculatory duct 3 parts of ejaculatory duct: Long, extra-prostatic Middle, intra-prostatic Distal, joining verumontanum in urethra Ejaculatory duct obstruction may be present in 5% of subfertile men
  • 7. Indications for TRUS in infertile males L ow ejaculate volume Z ero (azoospermia) or a decreased (oligospermia) number of sperm in the ejaculate S ignific a nt sperm motility abnormalities H istory of prostate infections, prostatitis
  • 8. Clinical suspicion of diagnosis of ejaculatory duct obstruction Azoospermia Hematospermia Painful ejaculation Perineal pain Urinary tract infections or trauma
  • 9. Causes of ejaculatory duct obstruction Seminal vesicle stones Mullerian duct (utricular) cysts Wolffian duct (diverticular) cysts Post-surgical scar tissue Post-inflammatory scar tissue Calcification (stone) near the verumontanum Congenital atresia Functional obstruction (alpha blocker, anti-psychotic, anti-depressants)
  • 10. Diagnosis of ejaculatory duct obstruction Azoospermia E jaculate volume <2.0 ml and a pH<7.2 that contains no sperm or fructose. Normal serum FSH and testosterone. Testicular of normal size (20cc) and consistency.
  • 11. TRUS diagnosis of ejaculatory duct obstruction D ilated seminal vesicles (>1.5 cm width) D ilated ejaculatory ducts (>2.3 mm) C yst, calcification or stones along the duct TRUS and seminal vesicle aspiration showing the presence of sperm in the seminal vesicle fluid within 2 days of ejaculation
  • 12. Technique Left lateral position DRE Introduction of rectal ultrasound probe No anaesthesia required Mild sedation for drainage or aspiration
  • 13. Transverse plane Prostate evaluation Base to apex Emphasis on base and mid prostate Seminal vesicle Small amount of urine in bladder is helpful
  • 15.  
  • 16.  
  • 17.  
  • 19. Prostatic cyst, infartion
  • 20. Sagittal Plane Bladder neck Urethra Verumontanum Ejaculatory duct Seminal vesicles, one at a time
  • 21.  
  • 24. D ilated ejaculatory ducts (>2.3 mm)
  • 25. D ilated seminal vesicles (>1.5 cm width)
  • 26. Aspiration from seminal vesicles or cysts Negative urine culture Mild sedation - midazolam Prophylactic antibiotics - 6 to 24 hours prior to aspiration e.g. ciprofloxacillin 500 mg - i/v gentamicin 160 mg before aspiration Continue oral antibiotics for another 3-5 days
  • 27. TRUS aspiration of utricular cyst
  • 28. TRUS – ejaculatory duct obstruction
  • 29. Conclusions TRUS is the ideal instrument for evaluation of ejaculatory duct disorders Fast replacing vasography Excellent planning for surgery Option of aspiration from seminal vesicle (diagnostic) or urticle cyst (therapeutic)