Unit testing and end-to-end (E2E) testing are important types of automated testing for JavaScript applications. Unit tests focus on testing individual functions or components in isolation to catch bugs, while E2E tests ensure that user flows work as expected by interacting with the application through a browser. The presentation discussed setting up testing frameworks like Karma and Jasmine for unit testing and Protractor for E2E testing. It also covered writing testable code, handling dependencies through dependency injection, and selecting elements and interacting with them during E2E tests.