Wave Optics of Chromosomes for the Remote Transfer of the Bioholographic Analogue of Aspirin

International Journal on Bioinformatics & Biosciences (IJBB) Vol 15, No.1, March 2025
DOI: 10.5121/ijbb.2025.15101 1
WAVE OPTICS OF CHROMOSOMES FOR THE
REMOTE TRANSFER OF THE
BIOHOLOGRAPHIC ANALOGUE OF ASPIRIN
Irene Caesar
President, Wave Genome LLC 30 Barstow Road, Unit SUPT, Great Neck,
New York 11021
ABSTRACT
Current medical treatment, including chemical pharmaceuticals, EMP treatments,
mRNA therapies, and genetic engineering via cutting and pasting DNA snippets do not
take into consideration the Structural Damage in Chromosomes they cause by
excessive chemicals, electromagnetic fields and homologous nucleotides, all of which
break the precisely calibrated geometry of a chromosome. And the Structural Damage
of Chromosomes is the major cause of all diseases. Extreme cases of the Structural
Damage in Chromosomes are turbo cancer, AIDS, sterilization and prion disease as
the ultimate case of encephalopathy. Thus, an urgent task of the biological science and
technology is to address the issue of the Structural Damage in Chromosomes. This task
includes the necessity of creating a fundamental theory of how the structure of a
chromosome operates, and a biotechnology that corrects and enhances the structure of
chromosomes. In this paper, I introduce my fundamental theory of Wave Optics in
Chromosomes, and the biotechnology of Bioholography for the correction of the
structural damage in chromosomes. Specifically, I introduce the theoretical and
technological paradigm of the Remote Transfer of the Bioholographic Aspirin
Analogue (aka Haspirin), including the results of the clinical trials conducted by my
company Wave Genome LLC at the Moscow State Bauman Technical University in
2017. Haspirin clinical trials had verified and confirmed my fundamental theory of
Wave Optics in Chromosomes.
KEYWORDS
wireless optogenetics, computational biophysics, structural genomics, scalar waves,
bioholography
1. WAVE OPTICS OF CHROMOSOMES
Current medical treatment, including chemical pharmaceuticals, EMP treatments, mRNA
therapies, and genetic engineering via cutting and pasting DNA snippets do not take into
consideration the Structural Damage in Chromosomes [1] they cause by excessive chemicals,
electromagnetic fields and homologous nucleotides [2], all of which break the precisely
calibrated geometry of a chromosome. And the Structural Damage of Chromosomes is the
major cause of all diseases. Extreme cases of the Structural Damage in Chromosomes are turbo
cancer, AIDS, sterilization and prion disease as the ultimate case of encephalopathy. Thus, an
urgent task of the biological science and technology is to address the issue of the Structural
Damage in Chromosomes. This task includes the necessity of creating a fundamental theory
of how the structure of a chromosome operates, and a biotechnology that corrects and enhances

2
the structure of chromosomes. In this paper, I introduce my fundamental theory of Wave Optics
in Chromosomes [3], and the biotechnology of Bioholography for the correction of the structural
damage in chromosomes [4]. Specifically, I introduce the theoretical and technological
paradigm of the Remote Transfer of the Bioholographic Aspirin Analogue (aka “Haspirin”),
including the results of the clinical trials conducted by my company Wave Genome LLC at
the Moscow State Bauman Technical University in 2017. The Bioholographic Analogue of
Aspirin was chosen on purpose, since it provides an easily verifiable model of clinical trials for
Wave Genome’s LLC Bioholography. The publication of the clinical trials results was delayed
on purpose, since till 2017, I have conducted other experiments with application of Wave
Genome’s LLC Bioholography to other health conditions, such as, for hematoma,
neurodermatitis, melanoma, and others. Haspirin clinical trials had verified and confirmed my
fundamental theory of Wave Optics in Chromosomes.
I have created the fundamental theory of Wave Optics in Chromosomes (1985-2010), based
upon my theory of Wave Crystals [5], which I had created in 1985, long before anybody in
the field of Bioholography [6]. My theory of Wave Crystals is the “theory of everything”,
and applies to any and every field of science. This theory states that the life-sustaining
information is nonlocal in time and space and is transmitted not via linear finite signals of
electromagnetic nature, but remotely and instantaneously via Refraction in the Wave
Crystals, which have one and only Focus of the Quantum Nonlocality / Zero Center of the
Zero Field, with this Zero Center being one and the same for chromosome and galaxy [7].
Instead of the term “Quantum Entanglement”, I have offered the term “Refraction Entanglement”
[8]. Wave Crystal is a Hologram, nonlocal in time and space, in such a way, that the Universe is
entirely in its every Matrix Point (the Holographic Principle). The Hologram is a specific
quality of a signal, so that the Holographic Signal contains an infinite number of frequencies,
particles and fields [9]. In 2012, I have formulated the Implication of the Holographic
Principle: “if the Universe is entirely in its every Matrix Point, then, every Matrix Point is
not simply different from any other Matrix Point, but is unique”. Therefore, every Wave
Matrix is both nonlocal and unique. And, with two exact copies of the same Wave Matrix,
we can transmit information between these two copies remotely and instantaneously, since,
in the Quantum Nonlocality, they constitute one and the same Systematic Whole [10].
I have applied my fundamental theory of Chromosomal Wave Optics to the research and
development in the field of Bioholography by my company Wave Genome LLC, which I have
founded in 2010, for the production of Digital Bioholographic Pharmacies; the remote
management of biosystems via laser signal; and the production of large-size and small-size
Generators of the Form for creating the scalar wave diffraction grating to deliver
Bioholographic Pharmacies. These Generators of the Form include electret-based wearables
(applicators aka “generators”); large-size MedBeds; and Helmets [11].
I was the first scientist to produce the electret-based applicators (aka “Psi-generators”) as being
coded by the individual human Wave Matrices; to treat these Wave Matrices as
Bioholograms; and to code the electrets with Bioholograms via lasers. The MedBed (RA
Sarcophagus) is the only medical bed on the market, which is based upon Bioholography, and is
operated by a green laser. My company was the first company to release Digital Pharmacies that
are based not upon EMPs, but upon the Zero Signal, produced by the laser-originated scalar
wave [12].
I have also created the concept of the Scalar Wave Capacitor, which combines an electret,
which produces a scalar wave, and a conductor as Biometal to prevent this scalar wave
from being self-extinguished. My company Wave Genome LLC, for example, had produced the
combination of Resveratrol and Bivalent Organic Selenium, which has much more cancer-

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preventive potency, than its Indian analogue of Resveratrol and Copper [13], since our nervous
system runs on selenium.
The Universe is 93% energy, and 7% particles, including cells and molecules. We are water for
85%. But this water / a liquid crystal media is only 7% of what we are. For 93%, we are
the wave crystal media / Wave Crystal. So, the crystal wave media (Wave Crystal) is the
basis for the liquid crystal media [14]. Between the cell division cycles, chromatin exists in
a chaotic state. But, during the cell division, chromatin literally crystallizes, forming two
chromatids, which form a chromosome [15]. The same gene is expressed in functional
species via a metacentric chromosome, and in dysfunctional individuals via an acrocentric
chromosome. The same gene is expressed via a metacentric chromosome in humans, and via an
acrocentric chromosome in monkeys [16]. A metacentric chromosome has the shape of an
equilateral cross, with isometry or the spatial translational symmetry; while an acrocentric
chromosome is half of a metacentric chromosome, and exhibits gross asymmetry [17]. A
metacentric chromosome is analogous to a well-centered and focused eye crystal, while an
acrocentric chromosome is analogous to a myopic or farsighted eye [18]. A chromosome is
a lens that allows our cells to focus the needed wave information during the cell division,
analogously to a crystal in our eye [19]. And, since the world is 93% energy, and only 7%
particles, this isometric lens is a specific wave interference pattern – a scalar wave
diffraction grating with certain Wave Optics, that is, Refraction towards the Focus of the
Wave Crystal [20].
Thus, the efficacy of our physiological processes, our functionality, longevity and reproduction
depend upon the structural isometry of our chromosomes during the cell division – upon
the ability to produce a coherent trigger-signal (a signal with a constant frequency), and a
scalar wave, based upon this coherent trigger-signal. The female gender chromosome is
metacentric. That is why a female is capable of giving birth. And the male gender
chromosome is acrocentric. That is why a male is not capable of giving birth. The male gender
chromosome is literally the destruction of the female gender chromosome. And, ultimately,
any structural damage in chromosomes leads to sterilization [21]. Only my fundamental
theory of Wave Optics in Chromosomes can explain why the structural damage in chromosomes
leads to sterilization, turbo cancer, AIDS and prion disease as the extreme case of
encephalopathy [22]. Also, only my fundamental theory of Wave Crystals can explain the
healing effect of spiritual practices, such as meditation or prayer. Meditation and prayer produce
a theta brain wave state, which is a coherent trigger-signal, capable of producing the scalar wave
diffraction grating with Refraction towards the Zero Center of the Zero Field / Focus of the
Quantum Nonlocality, one and the same for the chromosome and the galaxy [23].
Regeneration and clear vision are possible only in the theta brain wave state. The structural
damage of chromosomes in the brain leads to dementia. The opposite is also true: the effort
of producing the theta brain wave state leads to correction of the chromosomal structural
damage, affecting all the physiological systems remotely and instantaneously [24].
Since universe is holographic, we can record and transmit only holographic information
based upon Geometrical Optics of Chromosomes. Every biohologram is a tetrapole, with two sets
of opposite poles, as a self-sufficient systematic whole. Each pole is an inversion of the spin in
the integral torsion / torus. The inversion of the spin causes any external incoming linear
wave signal to reflect back upon itself, so that a scalar / standing wave emerges, when the peak of
the forward-going wave is nullified by the trough of the same wave when it is reflected upon
itself (as the result of the superposition of the peak of the incoming wave with the trough
of its reflected wave in phase opposition) [25].

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When the coherent trigger-signal is continuous enough, there emerges the scaling of the
scalar wave diffraction grating, when its every segment itself becomes a scalar wave, from
micro to macro dimensions, and vice versa, ad infinitum. The scaling results in the
emergence of Refraction, in accordance with the Refraction Code in this unique and
nonlocal Wave Crystal [26]. The scaling of the scalar wave diffraction grating explains the
nonlocal nature of the Biohologram, i.e., the ability to manage biological systems remotely
and instantaneously, including the remote instantaneous connection of all the cells and
molecules and atoms of our body. It also explains the existence of the a priori knowledge,
e.g., of the infinity, not available in empirical experience, and the importance of this a priori
knowledge for human regeneration, reproduction and general physiological wellbeing [27].
The scalar wave diffraction grating refracts the external linear signals towards the Zero
Center of the Wave Crystal / Hologram, analogously to the focus of the crystal in our
eye. Via changing the shape of the crystal (the lens), i.e., the Refraction within the
diffraction grating, our eye receives different information. And so do our chromosomes
[28]. DNA is self- protected from any external linear signal, since it is a paradigmatic
scalar wave (or a scalar wave generator), with one strand going one direction, and another
strand – the opposite direction. Again, the scalar wave annuls any external linear signal,
when the peak of the forward-going wave is annulled by the trough of the same wave,
when this wave is reflected back upon itself (in phase opposition). While the RNA is a single-
stranded spiral antennae, receiving external linear signals via expanding and contracting its spiral
step. Thus, the RNA is vulnerable to the external signals. The secret of Genome lies within
the shape of the RNA, as an inductor, which collects and stores energy in the form of the
magnetic field. Genetic enhancement is possible only if the RNA collects and stores the coherent
linear signals and long enough; and only if the DNA nullifies this signal in its scalar wave via
creating the spatial translational symmetry of metacentricity of the Holographic Signal, imposing
it upon the chromosomes during the cell division. The introduction of any homologous
RNAs will lead to the Effect of the Destructive RNA Interference, resulting in cell
apoptosis [29].
The totipotency of the Embryonic Stem Cells and their telomere regeneration instead of a
telomere shortening depend upon the activity of the X chromosome which is metacentric. The
Embryonic Stem Cell is a precisely calibrated Refraction Code at the Zero Center / Focus of the
Wave Crystal. The process of cell differentiation is a process of modulating the scalar wave
diffraction grating of the Embryonic Stem Cell Wave Matrix. We can increase the
regenerative and reproductive potency of the Embryonic Stem Cells, themselves, via
applying the Holographic Signal. The Holographic Signal is a coherent, impulse signal, reflected
upon itself within the resonator; and, then, refracted towards the Zero Center of the Wave
Matrix. As a result, the Holographic Signal gets modulated via the Embryonic Stem Cell of
a certain individual. The Holographic Signal is nonlocal and instantaneous in the Quantum
Biononlocality, and is the basis for the Remote Management of the Biosystems via the
Refraction Code of the Embryonic Stem Cell Wave Matrix. Wave Genome LLC was the first
company in the world to create the Digital Biohologram of various kinds of Stem Cells for the
Bioholographic Remote Stem Cell Therapy [30].
In the following I introduce in detail the Bioholographic Aspirin Analogue (aka Haspirin)
by my company Wave Genome LLC, as a paradigm of Bioholography for the recording
and remote transmitting of bioholograms via laser spectroscopy and coding electrets at nanolevel
via laser. The technology creates the “lenses” assisting our chromosomes in correcting their
Refraction for focusing genetic bioholographic information, both locally and remotely.

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2. WHY DO WE NEED THE BIOHOLOGRAPHIC DRUG (H-DRUG) OF
ASPIRIN?
Cardiologists around the world have come to a consensus on the advisability of prescribing
aspirin to patients with chronic ischemic heart disease [31]. According to all the current
recommendations, the use of aspirin as a platelet-aggregation inhibiting drug significantly
reduces the risk of developing cardiovascular dysfunction. Platelet-aggregation inhibiting
therapy is an important component of the primary and secondary prevention of cardiovascular
diseases and their complications. It is certainly justified to prescribe the platelet aggregation
inhibitors, for example, in acute coronary syndrome, because it is caused by the build-up of the
atherosclerotic plaque, and patients suffering from this disease always have thrombocytosis
of one degree or another. Obviously, without the use of antiplatelet drugs, effective
treatment of such patients is impossible. At present, taking aspirin for primary prevention is
considered to be justified when there is a high risk of complications of cardiovascular
diseases, in particular, a risk of myocardial infarction (in more than 45-50% of patients
during 10 years of observation).
It is simple enough to recognize such a patient: it is a smoking man or woman with excess
weight at the age of 45 and beyond, and with a blood pressure of 140/80, and their lipid
profile as follows: LDL-C 3.5 mmol / L, HDL-C 1.0 mmol / L. If such a patient quits
smoking and changes his/her lifestyle to a more health-oriented one (from changing their diet to a
regular physical exercise), the risk of developing myocardial infarction will be less than
10%.
The prescription of an antiaggregant therapy for the primary prevention should be addressed
each time individually, depending on the calculated risk of myocardial infarction and other
complications of vascular disease. The most effective is the use of the antiaggregant therapy by
patients with a history of stenting the coronary heart arteries of the heart and aortocoronary
bypass. Aspirin significantly reduces the risk of developing thrombosis; and in patients who
underwent a coronary intervention, shunts are even more vulnerable to thrombogenesis than
coronary arteries. The incidence of avoiding the failure of the cardiovascular system and
death for such patients is increased by aspirin from 37% to 55%. However, the long-term use of
acetylsalicylic acid drugs is often accompanied by the development of complications such as
gastritis, gastrointestinal ulceration or gastrointestinal bleeding, and other side effects [32].
Apparently, it is time to find an adequate substitute for aspirin. Wave Genome LLC had
created a bioholographic alternative to aspirin, which does not have overdose and/or side
effects issues; and had conducted clinical trials of the bioholographic aspirin. The study proved
the preventive therapeutic effect of a bioholographic drug comparable in its action with the
acetylsalicylic acid preparations. The results of the study demonstrated the advantage of
using a bioholographic drug in the treatment of patients with proven atherosclerosis in
comparison with aspirin due to the absence of overdose and side effects issues. The
bioholographic aspirin does not have a direct irritating effect on the gastric mucosa, and does
not undermine the positive role of thrombocytes in hemostasis for plugging and repairing
damaged blood vessels, thus preventing blood loss. The study has shown the safety of the
bioholographic drug for the patient. This means that a bioholographic aspirin is the only
alternative for patients with aspirin intolerance. The clinical trials tested the bioholographic
aspirin on patients with diabetes (3 cases), and a patient who had undergone the coronary
artery bypass grafting (1 case). These patients should be preferably prescribed a bioelectronic
aspirin.

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Another problem with aspirin is aspirin resistance [33]. According to various authors, it is
from 10 to 45%, while there is no resistance to the bioelectronic / bioholographic aspirin at all. In
addition, the bioelectronic aspirin does not interact with other drugs, as well as with alcohol.
Hence, the bioelectronic / bioholographic aspirin is not only comparable in effectiveness to
aspirin, but is surpassing its effectiveness and, to a large extent, its safety.
3. TECHNOLOGICAL MODEL FOR CREATING HASPIRIN – HOLOGRAPHIC
ANALOGUE OF ASPIRIN
Wave Genome LLC had conducted a pilot comparative study of the pharmacological platelet-
aggregation inhibitors of the Aspirin type and its analogues. Wave Genome LLC had
studied the chemical and physical properties of the preparations by various producers, and had
chosen Aspirin by Bayer (Germany) for its highest purity of the substance and lowest
deviation from the declared properties. Wave Genome LLC applied holographic
technologies in order to obtain its 3D model and transferred this model via both the analog
protocol and the digital protocol onto the media of the applicator chip. Wave Genome LLC had
also conducted the comparative study of various electret materials for the applicator chip. As
a result, Wave Genome LLC had selected an electret of natural origin. The transfer of
bioholographic information of the drug upon the applicator chip is as follows.
Wave Genome LLC had created the Holographic Aspirin Analogue / Haspirin, using a newly
invented Nonoptical Digital Holographic Microscope, which simplifies the operation of
a microscope, and makes it more ergonomic. This technology allows to record low signals
of a low-energy electron beam -- a total charge of 10 electrons, with a spatial resolution of
40 µm. The high quality of the registered holographic scalar wave interference of the
pharmacological preparation made it possible to convert it into a digital and analog model
with a reliable result.
The principle of this Digital Holographic Microscope operation consists in the recovery of the
complex amplitude of the wave in the plane of the observed object from its Hologram. The
Hologram is received via the superposition of the object beam and the reference beam.
But, instead of a photoelement, which requires a complicated photochemical processing,
Wave Genome LLC had used the matrix receiver of waves. In this case, the recovery of the
hologram is produced not in the physical, but in the virtual space with the help of the
mathematical models of the physical space. Up to date, many models of the Digital Holographic
Microscopes have so far been created, but all of them have a very complex structure with
lenses and the tuning mechanisms for focusing. At the same time, the models of the Digital
Holographic Microscopes without lenses have a too low resolution.
Wave Genome LLC was able to use a non-lens Digital Holographic Microscope with the
resolution at the same level as the Digital Holographic Microscopes with lenses due to using a
reference beam with a spherical wave front instead of a flat wave front. In this case, the
minimal half-period of the interference picture has the bigger size than the pixel of the matrix
receiver. And this had allowed us to register the Digital Hologram without any loss of
information. The main components of such a Digital Holographic Microscope are the
semiconductor laser; the digital CCD camera (Charge-Coupled Device); the optical fiber;
and the microoptic electromechanical phase modulator. If there is a need of recording the
Hologram of objects with different surface reflection coefficients, the device has the microoptic
electromechanical attenuator in both the reference beam and the object beam. Thus, the
construction of the Digital Holographic Microscope is greatly simplified, while the most
important role in its operation is played by the software. The transfer of the Hologram is

7
done via the USB interface. Lowering the size of the Holographic Microscope increases the
vibrational stability, and the precision of the Digital Holographic Microscope.
The operational scheme of the Digital Holographic Microscope is as following. The
optical fiber source of the beam is split into the reference beam and the object beam via the
optical fiber splitter. There might be an attenuator installed in order to record the Hologram
of the objects with different coefficients of transmission or reflection. For the reference
beam, there is the phase modulator installed for the possibility of changing different phases
between the reference beam and the object beam in the range of 0 to 360. The object beam goes
through the observed object, creating its diffraction image in the matrix receiver. At the
same time, the matrix receiver is subjected to the reference beam, which has the spherical wave
front, so that the Hologram is created in the matrix receiver.
The process of Holographic encoding goes in stages. The autocathode emits a coherent electron
flow. With voltage between the plate beneath the object under investigation (donor) and the
autocathode, the low energy electron beam of low energy reaches the object under study
(donor), and their interaction takes place. Most of the electron beam passes through the object
under study (donor) without changing (carrier wave), while a part of it interacts with the
atoms of the object under study (donor), changing the phase of the wave (a wave with a
changed phase). The remainder of the electron beam changes its direction after its
interaction with the object under study (donor). This part of the electron beam does not affect
the operation of the device and is not taken into account when obtaining an interference
image. The first two parts of the electron beam travel through the space to the detector of the
low-energy electron beam without any distortion from external influences. To eliminate such
external technogenic interference, the Digital Holographic Microscope has a two-component
permalloy camera – a mirror chamber as an internal cylinder, which protects the coherent
electron beam from the electromagnetic fields, eliminating any possible negative influences.
When a beam of electrons passes through the space between the object under investigation
(donor) and the detector of the low-energy electron beam, two electron waves (waves with a
modified phase and a reference wave) are superimposed, resulting in an interference
holographic image of the object under study. A low-energy electron beam detector is
installed at a distance of 10 cm from the substrate of the investigated object.
In the low-energy electron beam detector, the electron beam passes through two amplification
stages. First, it hits the microchannel plate of the MCP with a gain of 103. The amplified
flow after the MCP passes through the space to a phosphor screen, which is located at 1 mm from
the MCP. To obtain the necessary amplification, an additional voltage is applied between the
MCP and the phosphor screen. The amplified electron beam falls on the phosphor screen, on
which a luminescence appears, allowing the registration of an interference pattern. Using a
fiber optic disk, as the base of the phosphor screen, allows to eliminate any undesirable
light rays scattering. The resulting interference pattern of the object under investigation is
transmitted to a PC with special software that converts the interference pattern into a
holographic three- dimensional image of the object under study.
At the same time, a simultaneous digital and analog recording of the entire wave interference
spectrum takes place, which allows to study and archive the chemical characteristics of the
studied substance translated into an information-wave state. In addition to direct visual
recording of the entire spectrum on the phosphor screen, the detector unit of the holographic
microscope, operating via the low-energy electron beam, can be supplied with a CCD
matrix that makes it possible to receive a digital signal.

8
This technology was successfully tested by Wave Genome LLC in the Moscow State Bauman
Technical University laser laboratory in real time. As a result of the experiments, the
achievement of this biologically significant result was confirmed: the bioinformational value
of the holographic image of the object under study, and the ability to preserve the
information- wave characteristics in the transfer of these properties to the biosensors and
applicators.
4. CLINICAL TRIALS RESULTS FOR HASPIRIN – HOLOGRAPHIC ANALOGUE
OF ASPIRIN
The clinical trials were conducted in accordance with the government rules and regulations,
at the Moscow State Bauman Technical University clinic. The clinical trials have been
conduced for 14 days, as a blind experiment with two groups of 19 participants. In the
Study Group, eleven healthy volunteers were exposed to Haspirin: each participant was wearing
an electret- based applicator with Haspirin (Holographic Aspirin) encoded into the electret by
laser. In the Control or Placebo Group, eight healthy volunteers were exposed to the
placebo: each participant was wearing a non-electret applicator chip with no Haspirin.
There were thirteen male and six female participants, of whom at least six are women) under
the age of 30 years.
The clinical trials had proven the efficacy of Haspirin in the Study Group in comparison
with the Control Group receiving placebo. The Study Group had demonstrated a reliable
improvement in the functioning of the hematopoietic system and the rheological aggregate
blood states according to the results of biochemical, serological studies and the study of the
aggregate state and the functions of blood coagulation. At the same time, in the Placebo
Group, the studied indicators remained practically unchanged.
The clinical trials have been done on the healthy participants without any acute disease,
and without any acute exacerbation of a chronic disease, and who did not take any medication
for at least a week before the start of the clinical trials. An equal ratio of time exposure was
used for the Study Group and the Placebo Group.
Each participant signed the informed consent form for medical research and examinations.
Each participant’s examination took place three times a week. The examination consisted of
(1) a primary examination (medical examination; anthropometry; examination by the
cardiologist and electrocardiography; general blood analysis; general urine analysis; ultrasound of
internal organs; psychological testing, stress tests (Shtange, Ruffier-Dickson, Fukuda); (2) an
examination before the experiment (Thermometry; computer diagnostics of the activity of the
cardiovascular system; examination by a cardiologist); (3) an examination during the
experiment (computer diagnostics monitoring the activity of the cardiovascular system and
respiratory system; psychological testing; stress tests (Shtange, Ruffie-Dickson, Fukuda);
examination by the physician); and (4) a post-experiment examination (anthropometry;
electrocardiography; general blood analysis; general urine analysis; ultrasound of internal
organs; echocardiography; psychological testing; examination by the cardiologist).
The results of the clinical trials of the effect of Haspirin indicate that there is a tendency for
achieving even a greater degree of psychotherapeutic effect. It should be noted that
Haspirin, in terms of tolerability and the desire to continue, does not fundamentally differ
from the placebo effect, which indicates that the bioelectronic / bioholographic drug has no
detrimental components to provoke the negative subjective assessment. Besides its proven
antiplatelet results, Haspirin had also demonstrated the enhancement of other psycho-

9
physiological functions, including mental clarity.
Thus, the conducted clinical trials, supported by the technical tests of a laser, had proven
that the Haspirin bioelectronic / bioholographic drug produces an overall stimulating effect, and
enhances not only the blood antiaggregating processes, but also the other most important
protective functions of the human body. This allows us to conclude that Wave Genome’s LLC
technology for producing the bioelectronic / bioholographic drugs, like Haspirin, has great
potential for therapy, regeneration, and rejuvenation, as well as for enhancing human bodily
systems. Specifically, Bioholography with its use of scalar waves promotes the
synchronization of neural processes in the cerebral cortex and the elimination of the generators of
pathological excitation, as a harbinger of somatic disorders.
Also, Wave Genome LLC had unequivocally established not only the preventive antipletelet
effect of the Haspirin bioelectronic / bioholographic drug, its positive effect on the
hematopoietic system and general somatic state, but also its safety.
The results of this study are as follows.
The Holographic Method can be used to scan the properties and to obtain the characteristics
of the structures of complex molecules in real time for various tasks of medicine and
bioengineering, so as to create the bioelectronic / bioholographic drugs with specified properties
superior to the conventional pharmaceuticals.
Wave Genome’s LLC proven technology of Bioholography for Digital Bioholographic
Pharmacies and Bioholographic applicators (wearables), according to my fundamental theory of
Wave Optics in Chromosomes, can be used for avoiding the side effects and overdose issues
characteristic of the conventional medicine and pharmaceuticals. Bioholography is especially
important for solving conventional medicine and biology’s insolvable problems, allowing the
obtention and the transfer in real time of complex molecules structural properties, which are
undetectable by the devices used by the conventional medicine and biology. Bioholography
leads to the creation of new bioelectronic / bioholographic devices used for (1) detection and
recording; (2) archiving and editing; (3) transfer of the bioelectronic / bioholographic
information, based upon the digital files and the electret-based applicator-chips. The major
achievement of Wave Genome’s LLC Bioholography consists in solving the major problem of
healthcare: correcting the chromosomal structural damage by restoring the proper Chromosomal
Wave Optics.
The success in the conducted clinical trials of Haspirin had led us to the further development of
Bioholography, namely, to the application of Bioholography to the stem cells therapy, including
human embryonic stem cells and stem cells, extracted from the human epithelial cells. The
biological material was provided by the Bank of stem cells (the Prenatal Center of the Russian
Academy of Sciences and the Cryocenter LLC). Wave Genome LLC had studied stem cells

10
in the spectral range with a maximum possible capture (ultraviolet and low-intensity
infrared). And the entire complex of the stem cell properties was recorded using the
Bioholographic technologies. The 3D Stem Cell model was obtained (3D snapshot). And the
protocols for the editing, archiving and transfer were established via analog and digital
media.
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Chromosomes as Diffraction Grating for Focusing Genetic Information”, Proceedings of
Health 2.0 Asia 2016, the International Summit on Smarter Healthcare and Great Health
Industry, at the Invitation of the Chinese Government, November 9-10, 2016, Nanjing,
China. https://www.youtube.com/watch?v=FB3CczH9GsM
[5] Caesar I., (1985) “Wave Crystal”, Ivan Fyodorov Publishing House, St. Petersburg, Russia.
[6] Caesar I., (2012) “Matrix City and the Holographic Principle”, Proceedings of the Keynote
Lecture at the Harriman Institute of the Columbia University, New York.
[7] Caesar I., (2017) “Remote Management of Biosystems as Bioholography Based upon the Shape
of Chromosomes for Focusing Genetic Information”, Proceedings of the BIT’s 7th
Annual
World Congress of Molecular & Cell Biology, April 25-27, 2017, Xi’an, China.
[8] Caesar I., (2017) "Remote Biomedical Engineering via Mastering the Geometrical Optics of
Chromosomes", Speech as the Chair of the Neural Engineering Chapter, Proceedings of The
BIT’s 1st Annual World Congress of Biomedical Engineering, Editor: Fengxia Liang,
November 9-11, 2017, Xi’an, China. https://pmc.ncbi.nlm.nih.gov/articles/PMC5750607/
[9] Caesar I., (2017) “Remote Genetic Engineering as Bioholography Based upon the Shape of
Chromosomes, DNA and RNA for Focusing Genetic Information”, Proceedings of The 15th
World Gene Convention, November 13-15, 2017, Macao, China.
https://www.youtube.com/watch?v=nJZwNokyWAg
[10] Caesar I., (2018) “Remote Management of Biosystems via the Digitized Biohologram of the
Human Embryonic Stem Cell Based upon the Wave Optics of Chromosomes for Focusing
Genetic Information”, Proceedings of the 9th
Anniversary World DNA Day-2018, April 25-27,
2018, Dalian, China.
[11] Caesar I., (2018) "Digitized Biohologram of the Human Embryonic Stem Cell for the Remote
Management of Biosystems based upon Wave Optics in Chromosomes as Diffraction Grating
for Focusing Genetic Information", Proceedings of The Sixth National Symposium and the
Third International Academic Symposium of Bangkokthonburi University, May 20th
, 2018,
Bangkok, Thailand.
[12] Caesar I., (2018) “Remote Management of Biosystems via Holographic Embryo Based upon
the Wave Optics of Chromosomes as Modulated Scalar Wave Diffraction Grating” as Chair of
the “Role of Molecular & Cell Biology in Translational Medicine” Section, Proceedings of the
BIT’s 8th
Annual World Congress of Molecular & Cell Biology, October 14-16, 2018, Fukuoka,
Japan.
[13] Pilankar A., Singhavi H., Raghuram G.V., Siddiqui S., Khare N.K., Jadhav V., Tandel H., Pal
K., Bhattacharjee A., Chaturvedi P., Mittra I., (2022) “A pro-oxidant combination of resveratrol
and copper down-regulates hallmarks of cancer and immune checkpoints in patients with
advanced oral cancer: Results of an exploratory study”, (RESCU 004). Front. Oncol., 16
September, Sec. Molecular and Cellular Oncology, Vol.

11
12.https://doi.org/10.3389/fonc.2022.1000957.
[14] Caesar I., (2018) “Remote Drug Delivery via Modulating the Refraction in the Wave Optics of
Chromosomes”, Proceedings of The BIT’s 16th
Annual Congress of the International Drug
Discovery Science & Technology, November 6-8, 2018, Jinan, China.
[15] Caesar I., (2018) “Remote Management of Biosystems by Bioholography with its Mastering the
Wave Optics in Chromosomes as the Only Way of Stopping the Impending Genetic Collapse”
as Co- chair of the “Advances in Molecular & Cell Biology”, Proceedings of The BIT’s 9th
World Gene Convention, November 13-15, 2018, Singapore.
[16] Caesar I., (2019) “Remote Management of Biosystems via the Digital Biohologram of the Stem
Cell as the Wave Optics modulated by the Refraction Code in the Scalar Wave Diffraction
Grating” in the “Top Ten Innovative Regenerative Medicine” Chapter, Proceedings of The 13th
World Congress of Regenerative Medicine & Stem Cell, November 1-3, 2019, Dalian, China.
[17] Caesar I., (2021) Keynote Speech at the Keynote Forum “Remote Bioholography for Restoring
the Wave Optics of Chromosomes damaged by the SARS-CoV-2-caused autoimmunity”,
Proceeding of The World Biological Science and Technology Conference – BIOST 2021
Virtual, August 25-27, 2021. https://nexusnewsfeed.com/article/science-futures/world-biological-
science-and-technology-conference- 2021/
[18] Caesar I., (2021) “Remote Bioholography via the RNA Wave Modulation of Refraction Code
in the Wave Optics of the DNA Scalar Wave Diffraction Grating”, Proceedings of The 11th
Gene Convention, September 25-27, 2021, Dalian, China.
[19] Caesar I., (2021) “Holographic Stem Cell for the Remote Management of Biosystems”,
Proceedings of The BIT’s 14th
World Congress of Regenerative Med & Stem Cells 2021,
September 25-27, 2021, Dalian, China.
[20] Caesar I., (2022) “Theory of Wave Optics in Chromosomes as the Foundation for the Remote
Bioholography’, Proceedings of The World Conference on Biological Science and Technology
2022, Osaka, Japan.
[21] Caesar I., (2023) Keynote Speech at the Keynote Forum “Neural Bioholography as
Remote Management of Neural Wave Optics via Refraction in the Neural Scalar Wave
Diffraction Grating”, Proceedings of The 12th
Annual World Congress of Neurotalk 2023,
January 9-11, 2023, Sapporo, Japan. https://www.bitcongress.com/wce2023/
https://www.youtube.com/watch?v=J3VTFYBeEWY
[22] Caesar I., (2023) “Nonlocal DNA Wave Optics for the Remote Bioholography”, Proceedings of
The BIT’s 11th
Annual World DNA DAY-2023, April 25-28, 2023, Dalian, China.
[23] Caesar I., (2023) “Wave Optics of the Nonlocal DNA for the Remote Bioholography”,
Proceedings of The World Congress Systems Theory, Algebraic Biology, Artificial Intelligence:
Mathematical Foundations and Applications, June 26-30, 2023, Organized by the Russian
Academy of Sciences (RAS), National Academy of Sciences of Belarus (SCMAI RAS),
National Academy of Sciences of the Republic of Kazakhstan under the President of the
Republic of Kazakhstan (NAK), National Academy of Sciences of Tajikistan (NAT), Moscow,
Russia.
[24] Caesar I., (2023) “Remote Bioholography as Defense against Psychotronic Attack”, Bulletin of
East- Siberian Open Academy, No. 50.
[25] Caesar I., (2023) “Remote Bioholography for Managing Biosystems”, Bulletin of East-
Siberian Open Academy, No. 51.
[26] Caesar I., (2024) “Neural Bioholography via Neural Wave Optics in the Neural Scalar Wave
Diffraction Grating as Protection against Psychotronic Warfare”, Proceedings of The 14th
Annual World Congress of Neurotalk 2024, June 12-14, 2024, Budapest, Hungary.
[27] Caesar I., (2024) “Protection and preservation of the Wave Optics of Chromosomes for the
survival and development of the people”, Bulletin of East-Siberian Open Academy, No. 52.
[28] Caesar I., (2024) “Restoration of Wave Optics of Chromosomes as Biogenetic Safety”, Bulletin
of East-Siberian Open Academy, No. 53.
[29] Caesar I., (2024) “Wave Optics of Chromosomes and Bioholography as healthcare
foundation”,Bulletin of East-Siberian Open Academy, No. 54.
[30] Caesar I., (2024) “Bioholography of Quantum Nonlocality against Digital Immortality”,
Bulletin of East-Siberian Open Academy, No. 55.
[31] Schrör K., (1997) “Aspirin and platelets: the antiplatelet action of aspirin and its role in
thrombosis treatment and prophylaxis”, Semin Thromb Hemost., 23(4):349-56. doi: 10.1055/s-

12
2007-996108., PMID: 9263351 DOI: 10.1055/s-2007-996108.
[32] D'Agati V., (July 1996). "Does aspirin cause acute or chronic renal failure in experimental
animals and in humans?", American Journal of Kidney Diseases, 28 (1 Suppl 1): S24-9.
doi:10.1016/s0272- 6386(96)90565-x. PMID 8669425.
[33] Altman R., Luciardi H.L., Muntaner J. et al., (2004) “The antithrombotic profile of aspirin.
Aspirin resistance, or simply failure?”, Thrombosis J 2, 1, https://doi.org/10.1186/1477-9560-2-
1.
AUTHOR
Irene Caesar, Ph.D., is the Founder and President of Wave Genome LLC, company
which has pioneered Bioholography for the remote management of biosystems (founded
2010); Co-founder of “Matrix City” Consortium with the Institute for National Security
in Moscow for building self-sufficient human settlements based upon the remote
management of biosystems, climate and geophysical processes for the first time in the
history of humankind (founded 2012), presented in the Honorary Lecture at the
Harriman Institute of the Columbia University in September 2012; Co-founder of the Quantum Biointernet
for the remote rejuvenation via distant laser signal (May 2013); Colonel of Irkutsk Cossack Military,
awarded the Medal of Faith and Service to Russia (2014). Dr. Irene Caesar received her doctoral degree
from the Graduate Center of the City University in New York.

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